Hydroxypropyl yambuwe na FOLOULOSE (L-HPC) na hydroxypropyl selile (HPC) ni kogorwa na selile bikoreshwa cyane cyane muri farumasi, ibiryo nibindi bikoresho byinganda. Nubwo bahuriyeho mumibare nibisabwa, bafite itandukaniro ryingenzi mu rwego rwo gusimbuza, imitungo yumubiri, kudusaba, no gusaba.
1. Imiterere yimiti nurwego rwo gusimbuza
HydroxyProprilose (HPC) nigicuruzwa cyabonetse nyuma yo gutahura igice cya seliki, aho bimwe mumatsinda ya hydroxyl yasimbuwe namatsinda ya hydroxyPropyle. Urwego rwo gusimbuza (ubusanzwe rugaragazwa nkurugero rwa more yasimbuwe, ni ukuvuga umubare wa hydroxyProppoyl amatsinda ya hydroxyPropyl kuri glucose ishami ryibikoresho bya HPC) nikintu cyingenzi kigira ingaruka kumikorere ya HPC. HPC ifite urwego rwo hejuru rwo gusimbuza, mubisanzwe hagati ya 3.0 na 4.5, bivuze ko ibyinshi mumatsinda ya hydroxyl yasimbuwe namatsinda ya hydroxyProppoyl.
Hydroxypropylceppepylcelllcells (L-HPC) yateguwe binyuze muburyo busa bwambukiranya, ariko urwego rwabasimbuye ni hasi, mubisanzwe hagati ya 0.1 na 0.2. Kubwibyo, amatsinda ya hydroxyl ya L-HPC yasimbuwe gusa namatsinda mato ya hydroxyPropyle, hamwe numubare wamatsinda ya hydlexyle utazitiwe ni manini. Urwego rwo hasi rwo gusimbuza rutuma L-HPC itandukana na HPC mumico yumubiri na shimi.
2. Kukemera
Kubera itandukaniro murwego rwo gusimbuza, kukesha hpc na l-hpc byerekana itandukaniro rikomeye. HPC ni ugushonga amazi kandi irashobora gushonga mumazi akonje cyangwa ashyushye kugirango agire igisubizo gisobanutse neza. Ifite kandi umukenguruko mwiza mubinyabuzima bya polar. Uku kwigunga bituma HPC ikoreshwa nka solubilizer, umubyimba cyangwa umukozi wa dolling muri faruceuticals.
Ibinyuranye, L-HPC ifite imiterere itandukanye yo kugorana kubera urwego rwo hasi rwo gusimbuza. L-HPC ihujwe mumazi, ariko ifite ubushobozi bwiza bwo kubyimba amazi mumazi kandi irashobora gukora gel. Uyu mutungo wa L-HPC ubyemerera gukoreshwa nkikinyabupfura cyangwa kuzuza ibinini, bifasha ibiyobyabwenge kugirango bisuzugure vuba kandi birekurwe mumazi.
3. Imiterere yumubiri
HPC ubusanzwe igaragaza ubukuru bwo hejuru na filme-filt-film ihagaze kurwego rwo hejuru rwo gusimbuza no kwikeba. Ibisubizo bya HPC birashobora gukora filime zikomeye nyuma yo gukama kandi rero zikunze gukoreshwa mubice, firime yo gukora no gutwikira. Byongeye kandi, HPC ifite kandi ituze nziza cyane kandi irwanya peteroli, bigatuma habaho ibyifuzo bisaba imbaraga nziza z'umubiri no gushikama imiti.
L-HPC yerekana ubukuru bwo hasi hamwe namazi menshi yinjira kubera urwego rwo hasi rwo gusimbuza. Ubushobozi bwayo bwamazi hamwe numutungo mwiza wo kubyimba utanga ibyiza bidasanzwe mubikorwa bya tablet. L-HPC irashobora gukurura amazi no kubyimba, bityo bigateza imbere ibisate bya tablet no kurekura ibiyobyabwenge. Uyu mutungo usenyutse utera L-HPC ikoreshwa cyane nkutumva neza munganda za farumasi.
4. Ahantu ho gusaba
HPC ikoreshwa cyane muri farumasi, ibiryo, kwisiga hamwe nizindi mirima yinganda bitewe nubushobozi bwayo bwiza, imiterere-yubushobozi bwo kwishyuza. Mu murima wa farumasi, HPC ikunze gukoreshwa nkumubyimba, umukozi wa gelling, Solubilizer, ibikoresho bya membrane nibiyobyabwenge. Byongeye kandi, HPC nayo ikoreshwa mubiribwa nka Thickener na Emalifier, no kwisiga nkumukozi ushinzwe film na Moisturizer.
L-HPC ikoreshwa cyane munganda za farumasi, cyane cyane mugutegura ibinini. Nkibintu biteye isoni, birashobora kongera umuvuduko wo gusenyuka kw'ibisani no guteza imbere ibiyobyabwenge, bityo bigatuma ibinyabuzima bitera ibiyobyabwenge. Byongeye kandi, L-HPC irashobora kandi gukoreshwa nkuzuza na diluent kugirango utezimbere gukomera no gutuza ibinini.
5. Ingero zo gusaba
Mu nganda za farumasi, HPC ikoreshwa mugutegura igenzura ryagenzuwe. Irashobora kugenzura ibiyobyabwenge byibiyobyabwenge mugukora urujya n'uruza rwa Gel, bityo utanga igihe cyibiyobyabwenge. Porogaramu isanzwe harimo kugenzurwa abakozi bashinzwe kurekura ibisate byagutse hamwe na capsules.
L-HPC ikoreshwa cyane muburyo bwihuse-burekuye nkibisobanuro. Kurugero, mubihe bimwe byihuta birekura, hiyongereyeho L-HPC irashobora kugabanya cyane umwanya wibisate kugirango binjire mumubiri, bityo wihutishe gutangira ibikorwa byibiyobyabwenge.
6. Ingaruka y'ibidukikije n'umutekano
HPC na L-HPC ni ibinyomoro bikomoka kuri selile karemano bityo bikagira ubuzima bwiza bwa biodegradable hamwe nubucuti bwibidukikije. Zingizwa byoroshye mubidukikije kandi ntibigira ingaruka nke kubidukikije. Byongeye kandi, byombi bifatwa nkibikoresho bike kandi bikoreshwa cyane mugukora ibiryo na farumasi.
Nubwo hydroxypropyl selile ya selile (l-hpc) na hydroxyPropyl selile (HPC) byombi bihindura ibikomoka kuri selile, bitewe no gutandukanya ibintu byo gusimbuza, bifite ishingiro. Bitandukanye cyane. L-HPC ikoreshwa cyane mumwanya wa farumasi kubera imitungo yacyo nziza, mugihe HPC ikoreshwa cyane muri farumasi, ibiryo, kwisiga, kwisiga hamwe nizindi murima kubera ubwitonzi bwayo bwiza na firime. Itandukaniro riri hagati y'ibinyoma byombi mubyifuzo byurwego rwo gusimbuza kumiterere yumubiri nuguhindura, bityo bikaba bikaba bikwiranye na porogaramu zitandukanye.
Igihe cyagenwe: Gashyantare-17-2025