Ni irihe tandukaniro riri hagati ya HPMC na MHEC?

HydroxyPropyl Methylcellseliulose (HPMC) na methyl hydroxyAythyl. Nubwo gusangira ibintu muburyo bwabo nibisabwa, hariho itandukaniro ritandukanye hagati yombi.

1. Ibigize imiti:

HPMC (HydroxyPropyl Methylcellselse): HPMC ni polymer ya kimwe cya kabiri gikomoka kuri selile. Yakozwe binyuze mu guhindura imiti ya selile, yakuwe mbere na pompe cyangwa ipamba. Guhinduka bikubiyemo kuvura selile hamwe na alkali, bikurikirwa no gutoranya imyanda hamwe na methyl chloride kugirango itangire amatsinda ya hydroxyPropy na methyl kuri selile.

MHEC (methyl hydroxyyeryl selile selile): MHEC na hamwe ether na selile yabonye binyuze mu guhindura imiti ya selile. Bisa na HPMC, ihura nibyifuzo byo guhagarara kugirango utangire methyl na hydroxyerthyl matsinda kuri selile. MHEC ifata selile hamwe na alkali, ikurikirwa no guhinduka hamwe na methyl chloride na royone okiside.

2. Imiterere yimiti:

Mugihe HPMC na MHEC basangira umugongo wa selile, baratandukanye muburyo na gahunda yamatsinda asimburwa kuri iyi backbone.

Imiterere ya HPMC:
Amatsinda ya HydroxyPropyl (ch2chohch3) na methyl matsinda ya methyl (-ch3) yakwirakwijwe ku bushake urunigi rwa selile.
Ikigereranyo cya hydroxyPropyl kumatsinda ya methyl iratandukanye bitewe nigikorwa cyo gukora hamwe nibiranga.

Imiterere ya MHEC:
Methyl na HydroxyEythyl Amatsinda (-Ch2chohch3) yometse kuri selile.
Ikigereranyo cya methyl kumatsinda ya hydroxyerythyl irashobora guhinduka mugihe cya synthesi kugirango igere kumiterere yihariye.

3. Ibintu:

Umutungo wa HPMC:
HPMC yerekana amazi menshi yonyine, akora ibisubizo bisobanutse kandi bya viscous.
Ifite imiterere myiza ya firime, bigatuma iba isaba gushimisha film.
HPMC itanga ubushishozi bwiza no guhuza imitungo, yoza ubumwe muburyo butandukanye.
Ibyamamare bya HPMC Ibisubizo bya HPMC birashobora gutunganizwa no guhindura urwego rwo gusimbuza nuburemere bwa molekile.

MHEC Ibyiza:
MHEC irerekana kandi ibibazo byamazi, ariko kwikebagura birashobora gutandukana bitewe nurwego rwo gusimbuza nubushyuhe.
Ikora ibisubizo bisobanutse hamwe nimyitwarire ya pseudoplastique, ntagaragaza imitungo yoroheje.
MHEC itanga intambara nziza kandi ihamye ingufu muri sisitemu ya equeous.
Kimwe na HPMC, viscozetity yo ibisubizo bya Mhec irashobora kugenzurwa no guhindura urwego rwo gusimbuza nuburemere bwa molekile.

4. Porogaramu:

Porogaramu ya HPMC:
Inganda zubwubatsi: HPMC ikoreshwa cyane mumahanga ashingiye kuri sima, intoki zishingiye ku banyagasi, no gufatira neza kunoza ibikorwa, kugumana amazi, no kumeneka.
Farumasili: HPMC ikoreshwa mubyoroheje, igenzurwa-igenzurwa, ibisubizo bya Ophthalmic, hamwe nimyiteguro yibanze bitewe na firime yo gushiraho film na mucoadi.
Ibiryo no kwisiga: HPMC ikora nk'umukozi wijimye, Stabilizer, na Emalifie mu bicuruzwa, ibintu byita ku giti cye, no kwisiga.

Porogaramu ya MHEC:
Inganda zubwubatsi: MHEC isanzwe ikoreshwa muburyo bwo gucika bugufi nka Tile ashimishijwe, ahindura, kandi imbaraga zo kuzamura amazi, ibikorwa, no kumeza.
Irangi n'amakoti: MHEC ikoreshwa nk'urumono rufite amarangi ashingiye ku mazi, amabara, hamwe na inka zo kugenzura vino, irinde gusebanya, no kunoza imitungo ya porogaramu.
Ibikorwa bya farumasi: MHEC isanga porogaramu mu ihagarikwa ry'imiti, imyiteguro y'amaso, kandi igenzurwa-igenzurwa na dosiye yo kurekura nk'igituba kandi gihamye.

5. Ibyiza:

Ibyiza bya HPMC:
HPMC itanga imitungo yo gupima film, bigatuma bikwiranye no kumara kumeza no kugenzurwa-kurekura.
Iyerekana ko izoro nziza no guhambira ibiranga, kuzamura ubumwe bwamaterane itandukanye.
HPMC itanga uburyo bwo guhindura virusire no guhindura imitungo.

Ibyiza bya MHEC:
MHEC yerekana ingaruka zidasanzwe kandi zikagira ingaruka zidasanzwe muri sisitemu zingana, bigatuma ari byiza gushushanya, kubaka, hamwe nibikorwa bya farumasi.
Itanga imitungo myiza y'amazi, kunoza imikorere no kumeza mu bicuruzwa bishingiye ku bya sima.
MHEC itanga imyitwarire ya pseudoplastique, yemerera gusaba byoroshye no kunoza ibiranga ibice no gushushanya.

Mugihe HPMC na MHEC bombi bashiraho selile hamwe nibisabwa bisa, bagaragaza itandukaniro mubihangano byabo, imiterere, imitungo, nibyiza. HPMC izwiho gukora firime nziza na aphesion imitungo, mugihe Mhec irusha abandi kuba indabyimba, guhungabana, no kugumana amazi. Gusobanukirwa aya masano ni ngombwa kugirango uhitemo selile ikwiye kubisabwa byihariye munganda zitandukanye.