Gutegura n'umutungo wa HydroxyPropyl Methylcellse

Hydroxypropyl methylcellse. Nibikoresho byiza byibikoresho byo gutegura firime zo gupakira amazi.

Filime yo gupakira amazi ni ubwoko bushya bwibikoresho byo gupakira icyatsi, bwita cyane muburayi na Amerika nibindi bihugu. Ntabwo ari umutekano gusa kandi byoroshye gukoresha, ariko nanone bikemura ikibazo cyo gupakira imyanda. Kugeza ubu, film ihujwe n'amazi cyane cyane gukoresha ibikoresho bishingiye kuri peteroli nka polyvinyl inzoga na polyethylene nkaibikoresho fatizo. Petroleum nigikoresho kidashobora kongerwaho, kandi ikoreshwa nini izatera ibura ry'amazi. Hariho kandi firime zifata amazi ukoresheje ibintu bisanzwe nkibice na proteyine nkibikoresho fatizo, ariko aya manywa afata amazi afite imitungo mibi. Muri iyi mpapuro, ubwoko bushya bwa firime yo gupakira amazi yateguwe nigisubizo cyo gukora firime ukoresheje hydroxyPropyl methylcellse nkibikoresho fatizo. Ingaruka zo kwibanda kuri firime ya HPMC hamwe nubushyuhe bwo gukora firime ku mbaraga za tensile, kurangira, byoroheje no kukecuruzwa amazi ya HPMC yaganiriweho. Glycerol, Sorbinol na Gltaraldehyde bakoreshejwe neza imikorere ya firime yo gupakira amazi ya HPMC. Hanyuma, kugirango wagure porogaramu ya HPMC ikoreshwa ryamazi ya HPMC mubipfunyika yibiribwa, Antiofy Antioxidant (AOB) yakoreshejwe mugutezimbere ibintu bya Antioxident bya firime yo gupakira amazi ya HPMC. Ibisubizo nyamukuru ni ibi bikurikira:

(1) Hamwe no kwibanda kuri HPMC Iyo icyerekezo cya HPMC ari 5% kandi filime ikora ubushyuhe ni 50 ° C, imiterere yuzuye ya firime ya HPMC nibyiza. Muri iki gihe, imbaraga za kanseri ni nko 116mpa, kwihitiramo ku ya 31%, gufatanya ni 90%, kandi igihe cya manda ni 55min.

. Iyo ibikubiye muri Glycerol biri hagati ya 0.05% na 0.25%, ingaruka nibyiza, no kurera ibiruhuko byamazi ya HPMC igera kuri 50%; Iyo ibikubiye muri sorbittool ari 0.15%, kwihirika ku kiruhuko byiyongera kuri 45% cyangwa irenga. Nyuma ya HPMC y'amazi yo gupakira amazi yahinduwe hamwe na Glycerol na Sorbinool, imbaraga za tensile na optique byagabanutse, ariko kugabanuka ntibyari ngombwa.

. Iyo kongeramo glutaraldehyde yari 0.25%, imiterere ya mashini na optique yimitungo ya firime yageze kumubiri. Iyo kongeramo glutaraldehyde yari 0.44%, igihe gishongeshejwe amazi cyageze kuri 135 min.

. Iyo 0.03% Aob yongeyeho, firime ya AOB / HPMC yari ifite igipimo cya 89% kuri DPPH yubusa, kandi ni byiza cyane, kandi ibikundwa 61% byatejwe imbere cyane.

Amagambo y'ingenzi: Filime yo gupakira amazi; HydroxyPropyl Methylcellse; Plastizer; Guhuza Umukozi; Antioxydant.

Imbonerahamwe

Incamake ................................................. ...................................................... ............................................. .i

Abstract ...................................................... ...................................................... ................................. ii

Imbonerahamwe Ibirimo ................................................. ...................................................... .............................. i

Igice cya mbere Intangiriro .............................................. ...................................................... ............... ..1

1.1Ibikoresho byamamaza- Ibirimo ...................................................... ...................................................................... ............... .1

1.1.1Polyvinyl inzoga (pva) firime yo gukosora amazi ................................................ ..................... 1

1.1.2Pelyithylene oxide (peo) film yo gukosora amazi ................................................ .............2

1.1 .3

1.1.4 Filime ishingiye ku mazi ya poroteine ​​................................................ ....................................... .2

1.2 hydroxyPropyl methylcellse ................................................... .. ............................................................. 3

1.2.1 Imiterere ya hydroxyPropyl methylcellse ........................................................ ............... .3

1.2.2 Kukegura amazi ya hydroxypropyl methylcellse ........................................................ ............ 4

1.2.3 Imiterere yo gukora firime ya hydroxypropyl methylcellse ..................................................... .4

1.3 plastifisation yo guhindura hydroxypropyl methylcellse film .................................... ..4

1.4 Guhuza Guhuza HydroxyPropyl methylcellse film .................................... .5

1.5 Umutungo wa Antioxima wa HydroxyPropyl Methylcellse film ........................................ 5

1.6 Icyifuzo cyinsanganyamatsiko .............................................................. ................................................ .7

1.7 Ibirimo ................................................ ...................................................... .................. ..7

Igice cya 2 Kwitegura n'umutungo wa HydroxyPropyl Methyl Methyl Film Cleaken .................................................... ...........................

2.1 Intangiriro ................................................ .............................................................. .............................. 8

2.2 Icyiciro Cyambere ...................................................................... ................................................ .8

2.2.1 Ibikoresho byubushakashatsi nibikoresho ...................................................................... ......... ..8

2.2.2 Kwitegura neza ................................................ ....................................................................... ..9

2.2.3 Kuranga no Kwipimisha Imikorere ............................................. .. ........................... .9

2.2.4 Gutunganya amakuru ................................................. ...................................................... .................. 10

2.3 Ibisubizo hamwe nibiganiro ................................................ .............................................................. ......... 10

2.3.1 Ingaruka zo gukora firime yerekana firime yoroheje ya HPMC .............................. .. 10

2.3.2 Ingaruka zubushyuhe bwa firime kuri HPMC Films Films yoroheje ya HPMC ........................................ ...........................................................................................................................13

2.4 UMUTWE WA GIST ................................................ ..................................................... .. 16

UMUTWE WA 3 Ingaruka za Plastiziners kuri FILS-Yoroheje Amazi Yapakiwe Amazi .............................................................................................. ..17

3.1 Intangiriro ............................................................. .............................................................. 17

3.2 Igice cya none ...................................................... .............................................................. ......... ..17

3.2.1 Ibikoresho byubushakashatsi nibikoresho ................................................ ................................. 17

3.2.2 Gutegura amanota ................................................ ................................. 18

3.2.3 Kuranga hamwe no Kwipimisha Imikorere ............................................. .. ........................ .18

3.2.4 Gutunganya amakuru ........................................................ ............................................. ..19

3.3 Ibisubizo nibiganiro ................................................ ................................................ 19

3.3

3.3

3.3.3 Ingaruka za Glycerol na Sorbinol kumurongo wa mashini ya FILMS ...........................................................................................................

3.3.4 Ingaruka za Glycerol na Sorbinol kumurongo wa optique ya firime ya HPMC ................................................................................................................................................................. 22

3.3.5 Ingaruka za Glycerol na Sorbinol kumazi yoroheje ya firime ya HPMC .......... 23

3.4 Umutwe Incamake ................................................ .............................................................24

UMUTWE WA 4 Ingaruka zo Kwirukana Ibikorwa bya FILS-Gupakira Amazi .................................................................................................................... 25

4.1 Intangiriro ............................................................. ......................................................... 25

4.2 Igice cya none ...................................................... ................................................ 25

4.2.1 Ibikoresho byubushakashatsi nibikoresho ................................................ ............... 25

4.2.2 Gutegura amanota ................................................ ..................................................... ..26

4.2.3 Kuranga hamwe no Kwipimisha Imikorere ............................................. .. ............ .26

4.2.4 Gutunganya amakuru .............................................................. ............................................. ..26

4.3 Ibisubizo hamwe nibiganiro ............................................................. ....................................... 27

4.3.

4.3.2

4.3.3 Ingaruka za GlUtAralddehyde kumazi yoroheje ya firime ya HPMC ..................... ..28

4.3.4 Ingaruka za Gltaraldehyde kumitungo ya mashini ya firime yoroheje ya HPMC ... 29

4.3.5 Ingaruka za Gltaraldehyde kumitungo ya optique ya firime ya HPMC ..................... 29

4.4 Umutwe Incamaka ................................................ ..................................................... .. 30

UMUTWE WA 5 Antioxidant HPMC y'amazi ya SPANIAL PROFUANG .............................. ..31

5.1 Intangiriro ............................................................. ............................................................... 31

5.2 Icyiciro Cyambere ...................................................... ............................................................... 31

5.2.1 Ibikoresho byubushakashatsi hamwe nibikoresho byubushakashatsi ...................................................... 31

5.2.2 Gutegura amanota ................................................ ............................................................ .32

5.2.3 Kuranga hamwe no Kwipimisha Imikorere ............................................. .. ................................... 32

5.2.4 Gutunganya amakuru ........................................................ ............................................................ 33

5.3 Ibisubizo n'Isesengura ................................................ .............................................................. ............... .33

5.3.1 Isesengura rya FT-IR ................................................ .............................................................. ............ 33

5.3.2 xrd isesengura ................................................ .............................................................. .........

5.3.3 Antioxditent Ibintu ................................................ .............................................................. 34

5.3.4 Amazi yonyine ................................................ .............................................................. ............... .35

5.3.5 Ibintu bya mashini ................................................ .............................................................. ..36

5.3.6 Imikorere ya Optique ...................................................... ................................................ 37

5.4 Umutwe Incamake ................................................ .............................................................. ......... .37

UMUTWE WA 6 Umwanzuro .............................................................. .......................................... ..39

Reba ................................................ ...................................................... ................................. 40

Ubushakashatsi bujyanye no kwiga muri dost ................................................ .............................. ..44

Gushimira ................................................ ...................................................... ..................46

UMUTWE WA MBERE

Nkibimenyetso bishya byapakira ibikoresho, firime yo gupakira amazi yakoreshejwe cyane mugupakira ibicuruzwa bitandukanye mumahanga (nka Amerika, Ubuyapani, nibindi) [1]. Filime yo gukosora amazi, nkuko izina ribisobanura, ni firime ya pulasitike ishobora guseswa mumazi. Ikozwe mubikoresho bya polyment byamazi bishobora gusesa mumazi kandi byateguwe nuburyo bwihariye bwo gushiraho firime. Bitewe nibintu byihariye, birakwiriye cyane kubantu gupakira. Kubwibyo, abashakashatsi benshi kandi benshi batangiye kwitondera ibisabwa byo kurengera ibidukikije no kuvuha.

1.1 Filime yo gukosora amazi

Kugeza ubu, film ihuriweho n'amazi ahanini hamwe na firime zifata amazi ukoresheje ibikoresho bishingiye kuri peteroli nka polyvinyle oIlvinyne nk'ibikoresho fatizo, hamwe na firime zifatika zikoresha ibintu bya kamere nk'urusimba na poroteyine nk'ibikoresho fatizo.

1.1.1 Polyvinyl Inzoga (Pva) firime-yo gukosora amazi

Kugeza ubu, firime nyinshi ikoreshwa mumazi kwisi ahanini ni firime ya Pva. Pva ni polymer ya vinyl ishobora gukoreshwa na bagiteri nk'isoko ya karubone n'isoko y'ingufu, kandi ishobora kubora mu bikorwa bya bagiteri na enzymes [3]], bihangana by'agateganyo, kurwanira amavuta meza [4]. Filime ya Pva ifite imiterere nziza, guhuza n'imihindagurikire y'ikirere no kurengera ibidukikije. Byakoreshejwe cyane kandi bifite urwego rwo hejuru rwubucuruzi. Kugeza ubu ikoreshwa cyane cyane na firime nini yo gupakira amazi kumasoko [5]. Pva ifite imbaraga nziza kandi irashobora kugenwa na mikorobe yo kubyara CO2 na H2O mu butaka [6]. Byinshi mubushakashatsi kuri firime-yo gufunga amazi ubu ni ukuhindura no kubihuza kugirango ubone firime nziza. Zhao Linlin, Xiong Hanguo [7] Yize gutegura itegurwa rya firime yo gupakira amazi hamwe na PVA nkibikoresho nyamukuru bya ORTHOGNAL: Oxcel 5%, Sodium Dodecyl Sulfate (SDD) 4%. Nyuma yo kumisha ya microwave ya firime yabonetse, igihe cyo gufunga amazi mumazi yubushyuhe bwicyumba ni 101s.

Gucira urubanza uko ibintu bimeze ubu, firime ya Pva ikoreshwa cyane, ikiguzi gito, n'indashyikirwa mu buryo butandukanye. Nibintu byuzuye byamazi byoroshye ibikoresho kuri ubu. Ariko, nkibikoresho bishingiye kuri peteroli, Pva ni umutungo udasubizwa, kandi inzira yumusaruro mvugo irashobora kwanduzwa. Nubwo Amerika, Ubuyapani n'ibindi bihugu byashyize ku rutonde nk'ibintu bitari uburozi, umutekano wacyo uracyakinguye. Byombi guhumeka no kwinjizwa byangiza umubiri [8], kandi ntibishobora kwitwa chimie yuzuye icyatsi.

1.1.2 Polyethylene oxide (peo) firime yo gukosora amazi

Polyethylene oxide, izwi kandi nka polyethylene okiside ya polyethylene, ni theiceplastique, polymer yashonga amazi ishobora kuvangwa namazi mubipimo byose byubushyuhe bwicyumba [9]. Imiterere yimiterere ya Polyethylene Oxide ni H - (- Och2ch2-) n-yewe, na misa ya molekoni ya molekori izagira ingaruka kumiterere yacyo. Iyo uburemere bwa molekilari ari murwego rwa 200 ~ 20000, byitwa polyethylene glycol (peg), nuburemere bwa molekile burenze 20.000 birashobora kwitwa abapolisi (peo) [10]. Peo ni ifu yera itemba, yoroshye gutunganya no gutunganya. Ubusanzwe firime zisanzwe zitegurwa wo kongeramo plastistizers, stabilizers hamwe nuzuza ibirango bya Peo binyuze muri transmoplastique [11].

Ibipimo bya Peo ni firime yo gukosora amazi hamwe namazi meza yoroshye kuri iki gihe, kandi peo ifite imiterere ihamye, ariko peo ifite ingaruka zidasanzwe, kandi ibikorwa byateguwe byimazeyo, kandi imirimo myinshi yo gutesha agaciro, kandi imirimo myinshi yo gutesha agaciro, kandi imirimo myinshi yo gutesha agaciro, kandi imirimo myinshi yo gutesha agaciro, kandi imirimo myinshi yo gutesha agaciro, kandi imirimo myinshi yo gutesha agaciro, kandi imirimo myinshi yo gutesha agaciro, kandi imirimo myinshi yo gutesha agaciro. Pva firime ubundi [12]. Byongeye kandi, Peo na we afite uburozi runaka, bityo rero ni gake ikoreshwa mubipfunyika yibicuruzwa [13].

1.1.3 Filime ishingiye ku mazi ashingiye ku mazi

Starch is a natural high molecular polymer, and its molecules contain a large number of hydroxyl groups, so there is a strong interaction between starch molecules, so that starch is difficult to melt and process, and the compatibility of starch is poor, and it is difficult to interact with other polymers. Byatunganijwe hamwe [14,15]. Amazi yoroheje ya Starch ni umukene, kandi bisaba igihe kirekire cyo kubyimba mumazi akonje, bityo, hakoreshejwe ibinyamisonga, bikunze gukoreshwa mugutegura amazi meza. Mubisanzwe, ibikatsi birahindurwa nuburyo bukoreshwa nuburyo bwo gushiramo, guhinduka, gushushanya, no guhuriza hamwe kugirango bahindure imiterere yumwimerere yimigabane, bityo bikabahuza kugirango uhindure imiterere yumwimerere yimigabane, bityo uhuza imiterere yumwimerere yimigabane, bityo uhuza imiterere yumwimerere yimigabane, bityo uhuza imiterere yumwimerere yimigabane, bityo uhuza imiterere yumwimerere yimigabane, bityo uhuza imiterere yumwimerere yimigabane, bityo uhuza imiterere yumwimerere yimigabane, bityo uhuza imiterere yumwimerere yumukino, bityo bigatera imbere amazi-abakemura ibibazo [7,16].

Menyekanisha abahanga mu matsinda ya Starch ukoresheje imiti cyangwa gukoresha ibimama bikomeye kugirango basenye imirongo ya salo ishingiye ku mikorere yahinduwe hamwe na Stoight Story ifite imitungo myiza ya firime. Ariko, ku bushyuhe buke, film ya Strarch ifite imiterere yubukanishi cyane nubucuruzi bubi, birakwiye rero gutegurwa no kuvanga nibindi bikoresho nka PVA, hamwe nagaciro kamwe ntabwo ari hejuru.

1.1.4 Amazi ashingiye kuri poroteine-akomeye

Proteine ​​ni ibinyabuzima bifatika Macromolecular ibintu bisanzwe bikubiye mu nyamaswa n'ibimera. Kubera ko ibintu byinshi bya poroteyine bidahujwe mumazi mugihe cyubushyuhe bwicyumba, birakenewe gukemura ibibazo bya poroteyine mumazi mubushyuhe bwicyumba kugirango bategure amazi ameze neza hamwe na porotenes nkibikoresho. Mu rwego rwo kunoza ibibazo byoroheje bya poroteyine, bakeneye guhinduka. Uburyo busanzwe bwo guhindura imiti burimo gushushanya, Phthaloamidetion, FOSPHorylation, nibindi. Ingaruka zo guhindura ni uguhindura imiterere ya poroteyine, bityo ukugenda wiyongera, pelation, imikorere nkinyungu no gutuza byujuje ibyangombwa no gutunganya. Filime zishinzwe amazi ya poroteine ​​zirashobora gutangwa ukoresheje ibicuruzwa byubuhinzi na Staline nkabasambo byinyamanswa, cyangwa by'ubusangwabuhanga mu gukora ibikoresho bya peteroli nyinshi kugira ngo babone ibikoresho bya peteroli, kandi ibikoresho bishobora kongerwa kandi bikagira ingaruka nke ku bidukikije [19]. Nyamara, firime-yo gukosora amazi yateguwe na poroteyine imwe nkuko matrix ifite imitungo mibi namazi yoroheje ku bushyuhe buke cyangwa ubushyuhe bwo mucyumba, bityo hashyizweho urwego rwabasabye ni bigufi.

Kuri uyu mucunga, ni usobanura cyane guteza imbere ibintu bishya, bishobora kongerwa amazi hamwe nibikorwa byiza byo kunoza ibitagenda neza kuri firime zifatika.

HydroxyPropyl Methyl Cellulose (HYDROXYPropyl Methyl Methyl Methyl Methyl Methyl Methyl Methyl Methyl Methilose, HPMC kubera ibikoresho bya polymer, ariko kandi bidafite ubutunzi, kandi bidafite agaciro, kandi umutungo muto wongerwa muri kamere [20]]. Ifite amazi meza no gukora firime, kandi afite ibisabwa mugutegura firime zo gupakira amazi.

1.2 HydroxyPropyl Methylcellse

Hydroxypropyl Methyl Cellulose (HydroxyPropyl Methyl Cellulose, HPMC for short), also abbreviated as hypromellose, is obtained from natural cellulose through alkalization treatment, etherification modification, neutralization reaction and washing and drying processes. Amazi-amwohererezanyaga. HydroxyPropyl Methylcellse ifite ibiranga bikurikira:

(1) Amakuru menshi kandi yongerwa. Ibikoresho fatizo bya hydroxypropyl methylcellse nicyo kigari kinini cyane kwisi, ari cyo mu buryo bushobora kuvugururwa.

(2) Ishuti ya gicuti na biodegradudatable. HydroxyPropyl methylcellse ntabwo ari uburozi kandi itagira ingaruka kumubiri wumuntu kandi irashobora gukoreshwa mubuvuzi ninganda zibiribwa.

(3) Uburyo butandukanye. Nka ibikoresho bya polymer ya polymer, hydroxypropyl methylcellse ifite amazi meza, gutatanya, kwinuba, imiti ya buri munsi, ibiryo hamwe nizindi mirima yinganda [21].

1.2.1 Imiterere ya hydroxypropyl methylcellse

HPMC iboneka kuri selile karemano nyuma ya alkalisation, nigice cya PolyhydroxyPropyl ether na methyl bakundwa na prokide ya proparlene na methyl chloride. Impamyabumenyi rusange ya HPMC Methitl ivugurura kuva kuri 1.0 kugeza 2.0, hamwe na hydroxyPropyl impuzandengo ya ScaltitPropYelepy iringaniye kuva 0.1 kugeza 1.0. Formulaire yayo irerekanwa ku gishushanyo 1.1 [22]

Kubera ingwate zikomeye zihuza hagati ya selile karemano Macronolecules, biragoye gusezerera mumazi. Kudashobora kuba umuhanga mu mazi byatejwe imbere cyane kuko amatsinda ya ether yatangijwe muri selile yangiritse, isenya amasuka atandukanye hagati ya molekile kandi yongera kukesha mu mazi [23]]. HydroxyPropyl MethylcellAlose (HPMC) ni hydroxyalkyl alkyl ivanze ether (21], Amatsinda ya HlucroxyRexy DIDXES arimo uburyo bwamatsinda ya selile. byuzuye kwerekana guhuza no gutanga umusanzu wa buri tsinda. -. -Itsinda ryanyuma-rifite akazi, urubuga rwimyitwarire ntirugomba kudakora nyuma yo gusimburwa, kandi ni mumatsinda magufi yubatswe [21]. Amatsinda ya Hydroxyl ku ruhererekane rushya rw'amashami yongeyeho mu gisizwe gisigaye cya Glucose gishobora guhindurwa n'amatsinda yavuzwe haruguru, bikaviramo imiterere igoye cyane ku rugero runaka.

1.2.2 Kukesha amazi ya hydroxyproppopyl methylcellse

HydroxyPropyl Methylcellse ifite imitungo myinshi ihamye kubera imiterere yihariye, izwi cyane kuri ayo mazi. Byarabyimbye mu gisubizo cya colloidal mu mazi akonje, kandi igisubizo gifite ibikorwa bimwe byo hejuru, gukorera mu mucyo hejuru n'imikorere ihamye [21]. HydroxyPropyl methylcellse mubyukuri ni etherlcese nyuma yubusa bwahinduwe nubuso bwa proplene kandi biracyafite amazi meza kandi amazi ashyushye mumazi yateye imbere. Methyl selile ikeneye gushyirwa kuri 0 kugeza 5 ° C kuminota 20 kugeza 40 kugirango ubone igisubizo cyibicuruzwa hamwe na virusi nziza [25]. Igisubizo cya HydroxyPropyl MethylcellAllle Igicuruzwa gikeneye gusa kuri 20-25 ° C kugirango ugere ku nyungu nziza kandi mucyo cyiza [25]. Kurugero, hydroxyproppopyl methylcellse (Granular form 0.2-0.5 mm) irashobora gushonga byoroshye mumazi yubukonje bwa 4% agera kuri 20000

1.2.3 Umutungo wa firime wa HydroxyPropyl methylcellse

HydroxyPropyl Methylcellse igisubizo gifite imitungo ihanitse ya firime, ishobora gutanga ibihe byiza byo gutwikira imiti. Filime yo kurohama yakozwe na ni ibara itagira ibara, impumuro mbi, ikomeye kandi igaragara [21].

Yan Yanzhong [26] Yakoresheje ikizamini cya orthogonal kugirango ikore iperereza kumiterere ya firime ya hydroxyproppopyl methylcellse. Gusuzuma byakorewe mu nzego eshatu hamwe n'ibitekerezo bitandukanye hamwe n'ubushakashatsi butandukanye nk'ibintu. Ibisubizo byerekanaga ko kongeramo 10% hydroxypropyl methylcellse mo 50% byagize ibintu byiza bya firime, kandi bishobora gukoreshwa nkibikoresho bigize film byarakaye.

1.1 plastiki kugirango uhindure hydroxypropyl methylcellse film

Nkimikoro karemano, film yateguye kuva kuri selile nkibikoresho fatizo bigira umutekano mwiza no gutunganya, kandi birimo bizima nyuma yo gutabarwa, bitagira ingaruka kubidukikije. Nyamara, firime zidateganijwe kuri clilm zifite uburemere, kandi selile irashobora guhindurwa no guhinduka.

. Ibisubizo byerekanaga ko kwihitiramo firime ya selile ya selile yatunganijwe na 36% na 50% mugihe igice kinini cya triethyl citrate na acetyl tetrabityl citrate yari 10%.

Luo Qiushui eth [28] yize ingaruka za plastiziners glycerol, aside hamwe na glucose kumitungo ya methylcellsells. Ibisubizo byerekanaga ko umubare munini wa methyl wa Methyl Membrane byari byiza cyane mugihe ibipimo bya glycel byari byiza cyane mugihe ibyo wongeyeho byari byiza muri glucose na acide yijimye ni 0.5%.

Glycerol ni ibara ritagira ibara, riryoshye, risobanutse, risobanutse, rifite uburyohe butandukanye, bizwi nka glycerin. Birakwiriye gusesengura ibisubizo bitangaje, byoroshye, Plastizers, nibindi birashobora gushonga hamwe namazi muburyo ubwo aribwo bwose, kandi igisubizo cyo hasi cya Glycero kirashobora gukoreshwa nkamavuta yoroheje kugirango akore uruhu. Isoni, ifu ya hygroscopique cyangwa ifu ya kristalline, flake cyangwa granules, impumuro. Ifite imirimo yo kwinjiza mu buryo buhebuje no kugumana amazi. Ongeraho gato mu gukora guhekenya amenyo na bombo birashobora kugumisha ibiryo byoroshye, kuzamura imitunganyirize no kugabanya uruhara no gukina uruhare rwumucanga. Glycerol na Sorbinool ni ibintu byo gufunga amazi, bishobora kuvangwa n'amazi akemuwe n'amazi [23]. Birashobora gukoreshwa nka plastizizeri kuri selile. Nyuma yo kongeraho, barashobora kunoza guhinduka no kwihitiramo firime ya selile. [29]. Mubisanzwe, kwibanda kubisubizo ni 2-5%, kandi ingano ya plastistizer ni 10-20% ya selile. Niba ibikubiye muri Plastizer ari hejuru cyane, ibara ryibintu bya Colloid dehydration bizaba ku bushyuhe bwinshi [30].

1.2 Guhinduka kwa MydroxyPropyl methylcellse film

Filime yo gukosora amazi ifite amazi meza, ariko biteganijwe ko yashonga vuba mugihe akoreshwa mubihe bimwe, nkumufuka upakira imbuto. Imbuto zipfunyitse hamwe na firime ifunguye amazi, ishobora kongera umubare urokoka imbuto. Muri iki gihe, kugirango arinde imbuto, ntabwo ziteganijwe ko film izashonga vuba, ariko film igomba kubanza gukina ingaruka zimwe na zimwe zigumana amazi ku mbuto. Kubwibyo, birakenewe kurangira amazi yo gukemura amazi ya firime. [21].

Impamvu yatumye HydroxyPropyl Methylcellellse ifite Amatsinda meza yitsinda rya Hydroxyle Methycellse iragabanuka, bityo bigabanya amazi yo kwikeba kwa firime ya hydroxyPropyl methylcelliulose, hamwe na crophhdes zizatanga imiti myinshi yimiti, ishobora no kunoza imitungo ya firime kurwego runaka. Igitabo cya Aldehs cyahujwe na hydroxyproppopyl methylcellse harimo gltoldehdehyde, glyoxehde, kandi gltoldehyde ifite amatsinda abiri yihuta, kandi glutaraldehyde afite aho yangiza ibintu. Birashinzwe umutekano, lundaldehyde muri rusange ikoreshwa nkumukozi uhuza abatanze. Umubare wubu bwoko bwumutungo wambukiranya imipaka mubisubizo muri rusange ni 7 kugeza 10% yuburemere bwa ether. Ubushyuhe bwo kuvura bugera kuri 0 kugeza 30 ° C, kandi igihe ni iminota 1 ~ 120 [31]. Guhuza imyuka bigomba gukorwa muburyo bwa aside. Ubwa mbere, acide idasanzwe cyangwa acide kama kama yongewe kumuti kugirango uhindure ph yumuti ugera kuri 4-6, hanyuma Ahantu hongerwaho kugirango usohoze reaction [32]. Acide yakoreshejwe harimo HCL, H2SO4, acide ya acetike, aside ya citric, nibindi nkibyo. Acide na Aldehyde barashobora kandi kongerwaho icyarimwe kugirango igisubizo gikemuke gihuza reaction yo guhuza PH [33].

1.3 Umutungo wa Antioxima wa HydroxyPropyl methylcellse firime

HydroxyPropyl Methylcellllse irakize mumikoro, byoroshye gushiraho firime, kandi ifite ingaruka nziza. Nkibiryo birinda ibiryo, bifite iterambere ryiterambere ryiterambere [34-36].

Zhuang Rongyu [37] yakoresheje hydroxypropyl methylcellse (HPMC) film itangwa na inyanya, hanyuma ikayibika inyanya, hanyuma ikayibika inyanya, hanyuma ikayibika inyanya, hanyuma ikayibika kuri tomato, hanyuma ikayibika kuri tomato, hanyuma ikayibika inyanya, hanyuma ikayibika kuri 20 ° C ku minsi 18 yo kwiga ingaruka zanyanya n'inyanya. Ibisubizo byerekana ko gukomera kw'inyanya hamwe na HPMC igiti cya HPMC kiri hejuru yibyo udakunda. Byagaragaye kandi ko filime irimbi ya HPMC ishobora gutinza amabara ahinduka inyanya kuva umutuku kugeza itutswe na 20 ℃.

[38 Synthesis Synthesiproppopyl MethylcellAll Methylcellse (HPMC) ibikorwa bya Antioxy on "Wuzhong" imbuto za Bayberry mugihe cyububiko bukonje. Ibisubizo byerekanaga ko imikorere yo kurwanya ibitero ya Bayberry ivuwe na firime ya HPMC yateye imbere, kandi igipimo cyo kubora mugihe cyo kubikamo cyagabanutse, kandi ingaruka za firime 5% zahoze ari nziza.

Wang Kaikai Et al. . Ingaruka z'ibikorwa. Ibisubizo byerekanaga ko riboflavin-igikomango cya HPMC-CPMC-CPMC-CYIZA CYIZA CYIZA CYIZA CYANGWA HPMC, bigabanye neza imbyaro zo mu mazi mugihe cyo kubika imbuto.

Mu myaka yashize, abantu bafite ibisabwa byinshi kandi birenze umutekano wibiribwa. Abashakashatsi bo mu rugo no mu mahanga bahinduye imitekerereze yabo mu bushakashatsi kuva inyongeramusaruro zo gupakira. Mugusweho cyangwa gutera antioxidants mubikoresho byo gupakira, birashobora kugabanya okiside y'ibiryo. Ingaruka z'igipimo cyo kubora [40]. Amitimaxdidants yahangayikishijwe cyane kubera umutekano wabo muremure ningaruka nziza mubuzima bwumuntu [40.41].

Antioxexdant yamababi (AOB kuri ngufi) ni antioxxident hamwe numugano udasanzwe imigano idasanzwe hamwe namazi meza. Yashyizwe kurutonde rwigihugu gisanzwe GB2760 kandi yemejwe na minisiteri yubuzima nka antioxydant ibiryo bisanzwe. Irashobora kandi gukoreshwa nkibiribwa byongerera ibikomoka ku nyama, ibicuruzwa byo mu mazi n'ibiryo byisa [42].

Izuba LINA ETC. [42] Yasuzumye ibice byingenzi nimitungo yibibabi by'imigano kandi bikatangiza gushyira mu bikorwa antiofsiday ba Antiofsidants mu biryo. Ongeraho 0.03% Aob kuri Mayodond nshya, ingaruka za Antioxident nicyo kigaragara muriki gihe. Ugereranije nubwato bumwe bwa Antiophenol Antionidants, ingaruka za Antioxident biragaragara ko ziruta iyo zibyayi polyphenol; Ongeraho 150% kuri byeri kuri MG / L, umutungo wa Antioxident hamwe nububiko bwinzoga byiyongera cyane, kandi byeri bifite umubiri mwiza numubiri wa divayi. Mugihe cyemeza ubwiza bwambere bwumubiri wa vino, biroroshye kandi uburyohe bwa aroma nubusambana byamababi [43].

Muri make, hydroxypropyl methylcellse ifite imitungo myiza ya firime hamwe nibikorwa byiza. Nibintu byatsi kandi bitesha agaciro, bishobora gukoreshwa nka firime yo gupakira murwego rwo gupakira [44-48]. Glycerol na Sorbinool ni plastizi y'amazi. Ongeraho Glycerol cyangwa Sorbinol kumurongo wa filime ya selile irashobora guteza imbere ubukana bwa firime ya hydroxyPropyl methylcellse, bityo yongera kwihitiramo ibiruhuko bya firime [49-51]. GlUТDLDEHIDE ni ibintu bikunze gukoreshwa. Ugereranije nundi aldehyde, birashinzwe umutekano, kandi bifite itsinda rya diadihehde muri molekile, kandi umuvuduko wo kugabanya umuhanda uhagaze neza. Irashobora gukoreshwa nkuwambukiranya imipaka ya hydroxypropyl methylcellse film. Irashobora guhindura amazi yo kutubakira firime, kugirango film ishobora gukoreshwa mubihe byinshi [52-55]. Ongeraho imigano ya Bamboo ibibabi kuri hydroxypropyl methylcellse film kugirango utezimbere imitungo ya hydroxypropyl methylcelliulose kandi wagure ibyo yakoresheje mubipfunyika.

1.4 Icyifuzo cyinsanganyamatsiko

Duhereye ku miterere y'ubushakashatsi ubungubu, film ifata amazi agizwe ahanini na Pva Films, Filime zishingiye kuri Starch na Steprary na poroteine-ishingiye ku mazi ashingiye ku mazi. Nkibikoresho bishingiye kuri peteroli, Pva na Peo ntabwo binubijwe, hamwe nuburyo bwo gukora bwibikoresho byabo bibisi birashobora kwanduzwa. Nubwo Amerika, Ubuyapani n'ibindi bihugu byashyize ku rutonde nk'ibintu bitari uburozi, umutekano wacyo uracyakinguye. Byombi guhumeka no kwinjizwa byangiza umubiri [8], kandi ntibishobora kwitwa chimie yuzuye icyatsi. Igikorwa cyo gutanga umusaruro gishingiye ku gikari hamwe na poroteyine-gishingiye kuri poroteyine nicyo kidafite ingaruka kandi ibicuruzwa bifite umutekano, ariko bifite ibibi byo gushiraho firime, kurengera, kandi byoroshye gutandukana. Kubwibyo, mubihe byinshi, bakeneye kwitegura bavanga nibindi bikoresho nka Pva. Agaciro kakoresha ntabwo ari hejuru. Kubwibyo, bifite akamaro gakomeye ko guteza imbere ibintu bishya, bishobora gukoreshwa amazi hamwe nibikorwa byiza kugirango utezimbere indero ya firime yo gukosora amazi.

HydroxyPropyl Methylcellse ni ibintu bya polymer polymer, ntabwo bikungahaye kubikoresho gusa, ariko nabyo birashobora bishoboka. Ifite amazi meza no gukora firime, kandi afite ibisabwa mugutegura firime zo gupakira amazi. Kubwibyo, iyi mpapuro irashaka gutegura ubwoko bushya bwa firime yo gupakira amazi hamwe na hydroxypropyl methylcellse nkibikoresho byo kwitegura, kandi ongeraho plastiting gahunda ikwiye (glycerol na sorbittittit). ) Methylcellse Film yo gupakira amazi ifite akamaro gakomeye kubisabwa nkibikoresho byo gupakira amazi.

1.5 Ibirimo

Ibirimo ubushakashatsi ni ibi bikurikira:

1) Filime yo gupakira amazi ya HPMC yateguwe nuburyo bwo gukora firime, kandi imitungo ya filime yasesenguwe no kwibanda ku mazi ya HPMC hamwe n'ubushyuhe bwo gushinga film ku mikorere ya firime yo gupakira amazi ya HPMC.

2) Kwiga ingaruka za Slycero na SORBITOL kumuntu wa mashini, ubwitonzi bwamazi na optique imiterere ya firime ya HPMC.

3) Kwiga Ingaruka za Glutaraldehyde Umukozi wa Cross-Guhuza Amazi Yongeyeho, Umutungo wa Mechanical hamwe na Optical Production ya HPMC y'amazi ya HPMC.

4) Gutegura AOB / HPMC y'amazi asohokana na firime yo gupakira. Kurwanya okiside, amazi yoroheje, imitungo ya mashini hamwe nibintu bya optique bya firime ya aob / HPMC byiringiwe.

UMUTWE WA 2 Kwitegura n'umutungo wa HydroxyPropyl Methyl Cellulose Amazi Yapakiwe Amazi

2.1 Intangiriro

HydroxyPropyl Methylcellse niko basanzwe bakomoka kuri selile. Ntabwo ari uburozi, idahumanye, ishobora kongerwa, ihamye imitima, kandi ifite amazi meza yo kwikebana no gukora firime. Nibishobora gusa gupakira amazi ibikoresho bya firime.

Iki gice kizakoresha hydroxyPropyl methylcellse nkibikoresho fatizo byo gutegura hydroxypropyl methylcelliulose hamwe nubushyuhe bwo gupakira amazi, no kwiga imiterere ya firime kuri firime, optique, hamwe namazi. Imitungo ya kirisiti ya filime yaranzwe na X-ray iratandukanye, n'imbaraga za kanseri, kurangira kandi haze ikizamini cya hydroxyPropyl methylcelliulose, ikizamini cya optique n'amazi yo kwishyurwa n'amazi.

2.2 Ishami rishinzwe ubushakashatsi

2.2.1 Ibikoresho byubushakashatsi nibikoresho

2.2.2 Gutegura amanota

1) Gupima: Gupima umubare runaka wa HydroxyPropyl methylcellse hamwe na elegitoroniki.

2) Guseswa: Ongeraho HydroxyProppopyl MethylcellProse ku mazi atesha agaciro, akangura ubushyuhe busanzwe, hanyuma ureke bihagaze mugihe runaka (defoamung) kugirango ubone ibitekerezo runaka. membrane fluid. Yateguwe kuri 2%, 3%, 4%, 5% na 6%.

3) Gushiraho firime: ① Gutegura Filime hamwe na Filime zitandukanye: Gukuramo Filime ya HPMC Ibisubizo bitandukanye mubirahuri, hanyuma ubishyire mu ifuru ryumuka kuri 40 ~ 50 °. HydroxyPropyl Methylcellse Film yo gupakira amazi hamwe nubwinshi bwa 25-50 μM iritegurwa, kandi film irashirwaho kandi ishyirwa mumasanduku yumisha kugirango akoreshe. ②ppeParation ya firime zoroheje kurubupfura bukoreshwa na firime (ubushyuhe mugihe cyumye kandi cyo gushinga film hamwe nisahani ya HPR. HydroxyPropyl Methylcellse Film yo gupakira amazi hamwe nubwinshi bwa 45 μm yashizwemo, kandi film iracibwa kandi ishyirwa mumasanduku yumisha kugirango akoreshe. Amazi yateguwe yateguye Methylcellse filfea-fagitire yo gupakira amazi yitwa hpmc film ya HPMC muri make.

2.2.3 Kuranga hamwe no gupima imikorere

2.2.3.1 Angle-Angle X-ray itandukanye (Xrd) gusesengura

Mugari-inguni X-ray itandukanye (xrd) gusesengura imiterere ya kirisiti yikintu kurwego rwa molekile. X-ray itandukanye ubwoko bwa Arl / Xtra bwakozwe na societe ya TherMo Arl mu Busuwisi bwakoreshejwe mubyemezo. Ibipimo byo gupima: Inkomoko ya X-Ray yari umukerungano wa Nikel-kα (40kv, 40ma). Inguni scan ni kuva 0 ° kugeza 80 ° (2θ). Scanning yihuta 6 ° / min.

2.2.3.2 Ibiranga

Imbaraga za tensile no kwihitiramo film zikoreshwa nkibipimo ngenderwaho byo gucira urubanza imiterere, hamwe nimbaraga za tensile (imbaraga za tensile) bivuga imihangayiko ntarengwa ya plastike, kandi igice ni MPA. Kurangiza kumena (Guhagarika Kuramya) bivuga igipimo cyo kwihitiramo igihe filime yamenetse kugeza uburebure bwambere, bwagaragaye muri%. Gukoresha The Instron (5943) Andika Miniature Maniature Imashini ya Tensile Yigenga ya Tessile ya Astron (SHAnghai) igerageza imitungo ya tensile, ikizamini cya 50, hitamo urugero rw'ubunini bwa tensile, hitamo urugero rw'imigezi ndetse n'ubutaka busukuye.

2.2.3.3 Ibiranga Optique

Ibyiza bya optique nikimenyetso cyingenzi cyerekana gukorera muri transparency film yapakiye, cyane cyane harimo no kwanduza no gukurura film. Gufata no gushora inyamu byapimwe ukoresheje testers ya trance. Toranya icyitegererezo hamwe nubuso busukuye kandi nta murama, ubishyire mu kizamini, ukosore hamwe nigikombe cya Suction, hanyuma upime urumuri rwo gufatanya no gupima film mubushyuhe bwicyumba (25 ° C na 50% RH). Icyitegererezo cyageragejwe inshuro 3 hamwe nibisanzwe byafashwe.

2.2.3.4 Amazi Kudakemurwa

Kata 30mm × 30mm film ifite ubunini bugera kuri 45μm, ongeraho 100ml y'amazi hejuru y'amazi akomeye, hanyuma upime igihe cyo gucika intege rwose [56]. Buri cyitegererezo cyapimwe inshuro 3 kandi impuzandengo ifite agaciro, kandi igice cyari min.

2.2.4 Gutunganya amakuru

Amakuru yubushakashatsi yatunganijwe na Excel kandi yateguwe na software yinkomoko.

2.3 Ibisubizo n'ibiganiro

2.3.1.

Igishusho.2.1 Xrd ya firime ya HPMC mubirimo bitandukanye HP

Ubugari-inguni x-ray itandukanye ni isesengura ryamateka ya kristaline kubintu bya molekile. Igicapo 2.1 Ese xrd itandukanijwe na firime yoroheje ya HPMC munsi yimyitozo itandukanye. Hano hari impinga ebyiri zitandukanye [57-59] (hafi ya 9.5 ° na 20.4 °) muri firime ya HPMC mu ishusho. Irashobora kugaragara mu ishusho ko hamwe no kwiyongera kwa HPMC, impinga itandukanye ya firime ya HPMC hafi 9.5 ° na 20.4 ° yongerewe imbere. Hanyuma, gukomeretsa, urugero rwa gahunda ya molekile (gahunda yatumijwe) bwa mbere yariyongereye bwa mbere hanyuma igabanuka. Iyo kwibanda ku 5%, gahunda itunganijwe ya molekile ya HPMC nibyiza. Impamvu yibintu byavuzwe haruguru birashobora kuba ibyo kwiyongera kwa HPMC, umubare wa Crystal Nucleic, kugirango ubone uburyo bwa HPM molecular buri gihe. Iyo ubushishozi bwa HPMC burenze 5%, xrd itandukanye na firime iteye ubwoba. Duhereye ku rutonde rwa molekile, iyo kwibanda kuri hpmc ari binini cyane, vino yo gukemura amashusho ari hejuru cyane, bigatuma habaho iminyururu ya firime cyane, bigatuma habaho iminyururu ya firime cyane, bigatuma habaho iminyururu ya firime cyane, bigatuma habaho iminyururu ya firime cyane, bityo bigatuma habaho iminyururu ya moleki.

2.3.1..

Imbaraga za tensile no kwihitiramo film zikoreshwa nkibipimo ngenderwaho byo gucira urubanza imiterere, kandi imbaraga za tensile zivuga imihangayiko mugihe filime itanga plaint. Kurambura kuruhuka nigipimo cyo kwimurwa muburebure bwambere bwa firime kuruhuka. Gupima imitungo ya mashini irashobora gusuzuma ibyifuzo byayo mumirima imwe.

Igishushanyo.2 Ingaruka Zibintu bitandukanye bya HPMC kubintu bya mashini ya firime ya HPMC

Kuva ku gishushanyo cya 2.2, impinduka zihindura imbaraga zikangu no kurambura hafi ya firime ya HPMC munsi yumuti ukabije wo gukora firime, birashobora kugaragara ko imbaraga za firime za HPMC zigenda ziyongera mbere yo kwibanda kuri firime ya HPMC. Iyo igisubizo c'amahoro ari 5%, imitungo ya firime ya HPMC nibyiza. Ibi ni ukubera iyo igihe cyakoranye na firime concentration ari hasi, ibisubizo byibasiwe ni bike, imikoranire hagati yiminyururu ya molecular, kandi molekile ntishobora gutegurwa muburyo buke, bityo molekile ntishobora gutegurwa muburyo buke kandi buke kandi buke kandi buke kandi bukennye; Iyo filme-ikora amashusho yikuramo ari 5%, imitungo ya mashini igera kumuntu mwiza; Mugihe kwibanda ku mazi yo gukora firime akomeje kwiyongera, kwiyongera no gukwirakwiza igisubizo birushijeho kugorana, hagabanijwe uburebure bwa firime ya HPMC [60], bikaviramo kugabanuka kwa firime ya HPMC. Kubwibyo, kwibanda kuri 5% ya firime ya HPMC-gushiraho firime nibyo bikwiranye cyane. Imikorere ya firime yabonetse nayo nibyiza.

2.3.

Muri firime zo gupakira, kwanduza urumuri kandi haze nibipimo byingenzi byerekana gukorera mu mucyo wa filime. Igishushanyo 2.3 cyerekana imigendekere yo guhindukira no gukurura firime ya HPMC munsi yuburyo butandukanye bwa firime. It can be seen from the figure that with the increase of the concentration of the HPMC film-forming solution, the transmittance of the HPMC film gradually decreased, and the haze increased significantly with the increase of the concentration of the film-forming solution.

Igishushanyo..3 Ingaruka zibintu bitandukanye bya HPMC kumutungo wa optique ya firime ya HPMC

Hariho impamvu ebyiri zingenzi: Icya mbere, ukurikije uko umubare wibanda ku cyiciro cyatatanye, iyo kwibanda cyane, umubare wibanze ugira ingaruka mbi kubikoresho bya optique y'ibikoresho [61]. Kubwibyo, hamwe no kwibanda kubitekerezo bya firime ya HPMC, ubucucike bwa firime buragabanuka. Guhinduka urumuri byagabanutse cyane, kandi umuhondo yiyongereye cyane. Icya kabiri, uhereye ku isesengura ry'imikorere yo gukora film, birashobora kuba kubera ko firime yakozwe nigisubizo cyo gukora film. Kwiyongera kubibazo byo kuremira biganisha ku kugabanuka k'ubusa bwa firime no kugabanuka kwimitungo ya optique ya firime ya HPMC.

2.3.

Amazi yoroheje ya firime yo gufunga amazi afitanye isano na film. Gabanya 30mm × 30mlm firime zakozwe hamwe na firime zitandukanye zikora ibishushanyo, hanyuma ushire akamenyetso kuri firime hamwe na "+" kugirango upime umwanya kugirango firime ibuze burundu. Niba film yapfunyitse cyangwa inkoni kurukuta rwa beaker, ihunga. Igishushanyo 2.4 nigishushanyo cyibitekerezo byamazi yoroheje ya firime ya HPMC munsi yuburyo butandukanye bwa firime. Birashobora kugaragara uhereye ku gishushanyo cyo kwiyongera kw'amazi yo kwibandaho, igihe cyo gukemura amazi cya Filime za HPMC ziba ndende, zerekana ko amafaranga yo kunyegura film ya HPMC igabanuka. Biratangaje ko impamvu ishobora kuba ko yiyongereyeho igisubizo cya firime ya HPMC, vino yimico ikomeza nyuma ya firime ya HPMC mumazi no kugabanuka kwamazi.

Igishushanyo..4 Ingaruka zibintu bitandukanye bya HPMC kumazi yoroheje ya firime ya HPMC

2.3.2 Ingaruka zubushyuhe bwa firime kuri firime yoroheje ya HPMC

2.3.2.1 Xrd ibishushanyo bya firime ya HPMC muri firime zitandukanye zikora ubushyuhe

Igishushanyo..5 xrd ya firime ya HPMC munsi ya firime zitandukanye zikora ubushyuhe

Igicapo 2.5 cyerekana imiterere ya Xrd ya firime ya HPMC muri firime zitandukanye zikora ubushyuhe. Impinga ebyiri zidasanzwe kuri 9.5 ° na 20.4 ° yasesenguwe kuri firime ya HPMC. Dukurikije ubukana bw'impinja zitandukanye, hamwe n'ubushyuhe bwo gukora filme, impinga itandukanye ahantu habiri kwiyongera kwa mbere hanyuma bigaca intege, kandi ubushobozi bwari bwiyongereye bwa mbere, hanyuma bugabanuka bwa mbere. Iyo ubushyuhe bwo gukora firime bwari 50 ° C, gahunda yatumijwe na molekile ya HPMC ukurikije ingaruka zubushyuhe kuri nucleine ni nto, kandi koroshya biragoye; Mugihe ubushyuhe bwo gukora firime bwiyongera buhoro buhoro, igipimo cyiyongera cyane, kugenda k'umunyururu wa molekili wihuta, urunikiro runini rutunganijwe neza mu buryo bworoshye, kandi biroroshye gukora kristu, bityo byoroshye ko ari kristation, bityo rero ko ari kristu izagera ku gaciro ntarengwa ku bushyuhe runaka; Niba ubushyuhe bwo gukora firime ari hejuru cyane, icyerekezo cya molekile ni urugomo cyane, gushingwa nucleus ya kristu biragoye, kandi gushiraho imikorere ya kirimbuzi ni bike kandi biragoye gukora kuri kristu [62,63]. Kubwibyo, inyamanswa ya firime ya HPMC yiyongera mbere hanyuma igabanuka hamwe no kwiyongera kwa firime zikora ubushyuhe.

2.3.2.2

Guhindura firime bikora ubushyuhe buzaba bifite imbaraga runaka kumiterere ya mashini ya firime. Igishushanyo 2.6 cyerekana impinduka zimbaraga za kanseri no kwihitiramo firime ya HPMC muri firime zitandukanye zikora ubushyuhe. Muri icyo gihe, yerekanaga inzira yo kwiyongera mbere hanyuma kugabanuka. Iyo filime ikora ubushyuhe bwari 50 ° C, Imbaraga za Tensile no kwihitiramo film ya HPMC yageze ku ndangagaciro ntarengwa, zari 116 MPA na 32%.

Igishushanyo.

Dukurikije uburyo bwa gahunda ya molekile, ni ubuhe buryo bunini bwa molekile, nibyiza imbaraga za tensile [64]. Kuva ku gishushanyo cya 2.5 Xrd. Iyo ubushyuhe bwa firime bufite 50 ° C, urugero rwa gahunda yatumijwe nimbaraga nini, bityo imbaraga za firime za HPMC ziyongera mbere hanyuma zigabanuka zabanza gukora ubushyuhe, kandi kugabanuka kwiyongera kwabanza gushinga ubushyuhe bwa 50 ℃. Kurambura mukiruhuko byerekana icyerekezo cyo kwiyongera mbere hanyuma ugagabanuka. Impamvu irashobora kuba ko kwiyongera k'ubushyuhe, gahunda ya molekile yabanje kwiyongera hanyuma igabanuka, hanyuma imiterere ya kirisiti ishyirwaho muri matrix polymer matrix idahwitse matrix. Muri Matrix, imiterere yumubiri yakozwe kumubiri yakozwe, igira uruhare runaka muguhagarika [65], bityo bigateza imbere umwanya wa firime ya HPMC kugirango tugaragare ubushyuhe bwa firime 50 ° C.

2.3.2.3

Igicapo 2.7 ni uguhindura umurongo wa optique film ya firime ya HPMC muri firime zitandukanye zikora ubushyuhe. Birashobora kugaragara uhereye ku ishusho ko hamwe no kongera film zikora ubushyuhe, imurikagurisha rya firime ya HPMC buhoro buhoro ryiyongera buhoro buhoro, haratangira kugabanuka buhoro buhoro, kandi buhoro buhoro igabanuka ryagiye, kandi imitungo ya optique ya firime ya HPMC yagiye buhoro buhoro.

Igishushanyo..7 Ingaruka zo gukora firime zikora ubushyuhe kumurongo wa Optique ya HPMC

Dukurikije ingaruka z'ubushyuhe na molekile y'amazi kuri film [66], iyo ubushyuhe buri munsi ya HPMC mu buryo bw'amazi yihamye, ariko HPMC iri mu kirahure. Gukorera film byerekana umwobo muri HPMC, hanyuma utatanye urema ku mwobo nyuma yo kurakara [67], bityo urumuri rwa firime ni ruto kandi haze ni hejuru; Nkuko ubushyuhe bwiyongera, ibice bya moleki bya HPMC bitangira kwimuka, ibyobo byashizweho nyuma yo gukoraho amazi, kandi umucyo wogutabanuka wiyongera, bityo rero umucyo uzagata [68], bityo umucyo woguta kuri firime uriyongera kandi haragabanuka.

2.3.2.4 Amazi yoroheje ya firime ya HPMC muri firime zitandukanye zikora ubushyuhe

Igishushanyo 2.8 cyerekana ko amazi yoroheje ya firime ya HPMC muri firime zitandukanye zikora ubushyuhe. Birashobora kugaragara mu ishusho igihe cyo gusaza cya firime ya HPMC yiyongera hamwe no kongera firime, ni ukuvuga, amazi yo kumererwa firime ya HPMC araba mubi. Hamwe no kwiyongera k'ubushyuhe bwo gukora firime, igipimo cyo guhumeka molekile y'amazi n'igipimo cya gelateri cyihuse, urujya n'uruza rw'imisozi rugabanuka, kandi rufite gahunda ya molekile iragabanuka, kandi ituma molekile nyinshi zinjira hagati ya molekile ya HPMC. Kugura amazi nabyo biragabanuka.

Igishushanyo..8 Ingaruka zo gukora firime zikora ubushyuhe kumazi yoroheje ya firime ya HPMC

2.4 Incamake y'iki gice

Muri iki gice, hydroxyPropyl methylcellse yakoreshejwe nkibikoresho fatizo kugirango bategure HPMC yamasoko yamazi yubucuruzi nigisubizo cyo gukora film. Ko hasesenguwe na firime ya HPMC yasesenguwe na XDM; Imitungo ya mashini ya HPMC y'amazi ya HPMC yageragejwe kandi isesengurwa na micro-electronic yipimishije micro-electronique ya tessile yo kwipimisha kuri HPMC yasesenguwe na firime yoroheje. Igihe cyo kuvura mumazi (igihe cyo gukurura amazi) gikoreshwa mugusesengura amazi yacyo. Imyanzuro ikurikira yakuwe mubushakashatsi bwavuzwe haruguru:

1) Imitungo ya firime ya HPMC yiyongereye bwa mbere hanyuma igabanukaho haba kwiyongera kwibanda ku gisubizo cyo gukora filime, kandi bwa mbere byiyongereye hanyuma igabanuka hamwe n'ubushyuhe bwo gukora film. Iyo kwibanda kumuti wa firime ya HPMC, habaye 5% kandi ubushyuhe bwo gukora firime bwari 50 ° C, imitungo ya mashini ni nziza. Muri iki gihe, imbaraga za kanseri ni nko 116mpa, no kurera ibiruhuko ari 31%;

2) imitungo ya optique ya firime ya HPMC igabanuka hamwe no kwibanda ku gisubizo cyo gukora filime, kandi buhoro buhoro kwiyongera no kwiyongera k'ubushyuhe bwo gukora film; ku buryo bumva neza ko kwibanda ku gisubizo cyo gukora film butagomba kurenga 5%, kandi ubushyuhe bwo gukora film butagomba kurenga 50 ° C.

3) Amazi yoroheje ya firime ya HPMC yerekanaga inzira yo hepfo hamwe no kwiyongera kwibanda kubisubizo bya firime no kwiyongera k'ubushyuhe bwa firime. Iyo kwibanda kuri 5% ya firime ya HPMC hamwe nubushyuhe bwo gukora firime ya 50 ° C yakoreshejwe, igihe cyangiza amazi cyari 55.

UMUTWE WA 3 Ingaruka za Plastizirs kuri HPMC Amazi Yapakiwe Amazi

3.1 Intangiriro

Nkubwoko bushya bwa polymer ibikoresho bya polymer HPMC-firime yo gupakira amazi ifite ibyiringiro byiza byiterambere. HydroxyPropyl Methylcellse niko basanzwe bakomoka kuri selile. Ntabwo ari uburozi, idahumanya, kongerwa, gihamye, kandi gifite imitungo myiza. Gukuramo amazi hamwe na firime, nibishobora gupakira amazi ibikoresho bya firime.

Igice kibanziriza iki cyaganiriye ku gutegura filfere y'amazi ya HPMC ukoresheje hydroxyproppopyl methylcellse nk'ubushyuhe bwo gukora film of the IldroxyPropyl Methylcellse Film yo gupakira amazi. Ingaruka z'imirimo. Ibisubizo byerekana ko imbaraga za kanseri ya filime zijyanye na 116mpa no kwirangira ni 31% munsi yubushake bwiza no kwibanda. Gukomera kwa firime nkiyi ni bibi muri porogaramu zimwe kandi zikeneye kurushaho gutera imbere.

Muri iki gice, hydroxyPropyl methylcellse iracyakoreshwa nkibikoresho fatizo, kandi film yo gupakira amazi yateguwe nigisubizo cyo gukora film. , kwihirika ku kiruhuko), imiterere ya optique (gucuruza, haze) n'amazi yoroheje.

3.2 Ishami rishinzwe ubushakashatsi

3.2.1 Ibikoresho byubushakashatsi nibikoresho

Imbonerahamwe 3.1 Ibikoresho byubushakashatsi hamwe nibisobanuro

Imbonerahamwe 3.2 ibikoresho byo kugerageza no gusobanura

3.2.2 Kwitegura

1) Gupima: Gupima umubare runaka wa HydroxyPropyl MethylcellProse (5%) na Sorbitpol (0,15%, 0,25%, 0.25%, 0.35%, 0.45%).

2) Guseswa: Ongeraho HydroxyProppopyl Methylcellrose mu mazi atesha umutwe, akangura ubushyuhe busanzwe n'igitutu kugeza igihe yashongeshejwe rwose, hanyuma yongeraho glycerol cyangwa imyenyeri mu bice bitandukanye. Muri hydroxyPropyl methylcellse igisubizo, karatuze mugihe cyigihe cyo kuvanga neza, kandi ureke bihagarare muminota 5 (defoaming) kugirango ubone ibitekerezo bimwe byamazi agenewe firime.

3) Gukora film: Gutera amazi yo gukora firime mubirahuri hanyuma uyishyireho kugirango ugire umwanya wo gukama no gukora film yo gukama no gukora firime yo gukama no gukora filime ya 45 μm. Nyuma ya firime ishyizwe mumasanduku yumisha kugirango akoreshe.

3.2.3 iranga hamwe no kwipimisha imikorere

3.2.3.1 Kwinjira kwa Infrarod (FT-IR)

Kugereranya kwanga (FTRIR) nuburyo bukomeye bwo kuranga amatsinda akubiye mumiterere ya molekeland no kumenya amatsinda yimikorere. Imyitozo yo kwinjiza infrared ya firime yo gupakira HPMC yapimwe hakoreshejwe nicolet 5700 ihinduranya amanota ya enterineti yakozwe na TheRoelectric Corporation. Uburyo bwa filime yoroheje bwakoreshejwe muri ubu bushakashatsi, intera ya scaning yari cm 500-4000, 1-4, kandi umubare wa scanning wari 32. Films Film yarumiwe mu kigero cyumye kuri 50 ° C kuri 24 h kubireba 24 H kubireba 24 h.

3.2.3.2 Mugari-angle X-ray itandukanye (Xrd) gusesengura: kimwe na 2.2.3.1

3.2.3.3 Kugena imiterere ya mashini

Imbaraga za tensile no kwihitiramo ibiruhuko bikoreshwa nkibipimo byo gucira urubanza imiterere yacyo. Kurambura kuruhuka nigipimo cyo kwimurwa muburebure bwambere mugihe firime yacitse, muri%. Ukoresheje instron (5943) Miniature Electronic Imashini Yibanze kuri Tensile Yibiciro bya Interron (SHAnghai) Ibizamini bya GB13022-92.

3.2.3.4 Kwemeza imiterere ya optique: kimwe na 2.2.3.3

3.2.3.5 Kwiyegurira Amazi Kudakemurwa

Kata 30mm × 30mm film ifite ubunini bugera kuri 45μm, ongeraho 100ml y'amazi hejuru y'amazi akomeye, hanyuma upime igihe cyo gucika intege rwose [56]. Buri cyitegererezo cyapimwe inshuro 3 kandi impuzandengo ifite agaciro, kandi igice cyari min.

3.2.4 Gutunganya amakuru

Amakuru yubushakashatsi yatunganijwe na excel, kandi igishushanyo cyashushanijwe na software yinkomoko.

3.3 Ibisubizo n'ibiganiro

3.3.1 Ingaruka za Glycerol na Sorbinol kuri stroctrum ya infrared ya firime ya HPMC

(a) glycerol (b) Sorbinol

Igishushanyo

Kugereranya kwanga (FTRIR) nuburyo bukomeye bwo kuranga amatsinda akubiye mumiterere ya molekeland no kumenya amatsinda yimikorere. Igicapo 3.1 cyerekana ko Spectra ya Filime ya HPMC hamwe na glycerol zitandukanye na sorbitting. Irashobora kugaragara ku ishusho ko uruziga rwa skeleton ruranga film za HPMC ruri mu turere tubiri: 2600 ~ 3500 ~ 1750 ~ 1700CM-3419], 3418CM-1

Imitwe yinjira imbere iterwa no kurambura jye na yewe, 2935cm-1 ni amatsinda ya hydroxyle yibanze kandi ya kabiri. Kwinjira mu itsinda rya hydroxyl mu rujijo rwo kurambura urwego, 945cm-1 ni ugukubita amata ya -CH3 [69]. Impinga yuzuye kuri 1454cm-1, 1373cm-1, 1315cm-1 na 945cm-1 zahawe impaka zo guhindura ubusoni, 1 mu ndege no hanze yindege zinama za -CH3, 18. Nyuma yicishijwe bugufi, nta mpinga zishingiye ku buryo bushya bwa filmém ya film, byerekana ko HPMC itigeze ihindura ibintu by'ingenzi, ni ukuvuga, Plastizer ntabwo yangije imiterere yayo. Hamwe na Glycerol, kurambura hejuru ya -hh saa 3418cm-1 ya firime ya HPMC, kandi impinga ya-1CM-1, hamwe na --itsinda rya hydroxyle yibanze naya kabiri kandi ryagandukiye; Hiyongereyeho Irniton kuri firime ya HPMC, -Hoh irambuye impinga muri 3418cm-1 yagabanutse, kandi impinga yinjira muri 1657cm-1 yagabanutse. . Impinduka zibi zishingiye kuri izi ziterwa ahanini ningaruka za intero na hydrogène yimikorere yimikorere, bikaba bihinduka hamwe na begereye -ch3 na -ch2. Kubera gato, kwinjiza ibintu bya moleki bibuza gushiraho hydrogene yinzego ziterabwoba, bityo imbaraga za kanseri za firime zigabanya [70].

3.3

(a) glycerol (b) Sorbinol

Igishushanyo cya 3.2 xrd ya firime ya HPMC muri Glycerol zitandukanye

Mugari-inguni x-ray itandukanye (xrd) gusesengura ibintu bya kirisiti byibintu bya molekile. X-ray itandukanye ubwoko bwa Arl / Xtra bwakozwe na societe ya TherMo Arl mu Busuwisi bwakoreshejwe mubyemezo. Igicapo 3.2 Ese xrd ibishushanyo bya firime ya HPMC hamwe nibibazo bitandukanye bya Glycerol na Sorbinol. Hamwe na Glycerol, ubukana bwimpinga itandukanye kuri 9.5 ° na 20.4 ° bombi bagabanutse; Hiyongereyeho sorbinool, ubwo umubare wo kwiyongera wari 0.15%, impunzi zitandukanye kuri 9.5 ° zaragabanije, kandi zicaga intege cyane, ariko ubukana butandukanye, ariko ubukana butandukanye bwari munsi yubwa firime ya HPMC idafite SERBITOL. Hamwe no kongeraho kwiyongera kwa Sorbinool, impinga itandukanye kuri 9.5 ° yagabanutseho, kandi itandukana na 20.4 ° ntabwo yahindutse cyane. Ni ukubera ko hiyongereyeho molekile ntoya ya glycerol na sorbinol bihungabanya gahunda yo gutumiza iminyururu ya molekile kandi isenya imiterere yumwimerere, bityo bigabanya imiterere ya firime. Irashobora kugaragara ku ishusho Glycerol ifite uruhare runini kuri FROSTST Filime ya HPMC, yerekana ko Glycerol na HPMC bahuza neza, mugihe sorbitol na HPMC bafite imyumvire mibi. Duhereye ku isesengura ry'amashanyarazi, Irmalit ifite imiterere y'isukari isa n'iyandurika, kandi ingaruka za kigari ni nini, bituma habaho interpetike ikomeye, molekile ya selile, bityo igatangira gukurikizwa kuri charbilase.

[48].

3.3.3 Ingaruka za Glycerol na Sorbinol kumurongo wa maniction ya firime ya HPMC

Imbaraga za tensile no kwihitiramo film zikoreshwa nkibipimo kugirango ucire urubanza imitungo yayo, kandi gupima imitungo irashobora gusuzuma imiterere yacyo mumirima imwe. Igicapo 3.3 cyerekana impinduka mu mbaraga zidasanzwe no kwihitiramo firime ya HPMC nyuma yo kongeramo plastistizers.

Igishushanyo3

Irashobora kugaragara kuva ku gishushanyo 3.3 (a) ko hiyongereyeho glycerol, kurengerwa na firime ya HPMC yiyongera hanyuma igabanuka, mugihe imbaraga za tensivile zigabanuka bwa mbere, mugihe imbaraga za tensile zabanje kugabanuka vuba, hanyuma zikaba zigenda buhoro hanyuma zikomeza kugabanuka. Kurangiza firime ya HPMC yiyongereye bwa mbere hanyuma agabanuka, kuko Glycerol afite imitwe ya hydrophilike nyinshi, bigatuma molekile n'amazi ifite ingaruka zikomeye za hydration [71], bityo igira ingaruka zikomeye kuri film. Hamwe no kwiyongera guhoraho kwa Glycerol, kwihitiramo film ya HPMC igabanuka, ibi ni ukubera ko Glycerol ituma urunigi runini rwa HPMC rugabanuka, kandi ubwitonzi buba hagati ya Macronolecules, bityo film ihangayitse, bityo filime igabanuka, ikagabanya kurera kuri firime. Impamvu yo kugabanuka kwihuta cyane Imbaraga za Tensile ni: hiyongereyeho molekile nto ya glycerol ihungabanya uruhago rwa HPMC, bagabanya imbaraga zimikoranire hagati ya Macronolecules, kandi bigabanya imbaraga za kanseri ya macronolecules, kandi zigabanya imbaraga za kanseri, kandi zigabanya imbaraga za kanseri ya firime; Imbaraga za Tensile Ubwiyongere buke, ukurikije uruniko rwa molekile, ingendo za molecc zibangamiwe cyane, bigateza imbere iminyururu ya HPMC ku rugero runaka, biteza imbere gahunda ya moleculari ya HPMC ku rugero runaka, bigateza imbere iminyururu ya HPMC ku rugero runaka, biteza imbere gahunda ya polecular imwe, kandi ituma imbaraga za molegisi zigenda ziyongera gato; Ariko, mugihe hari glycerol ari byinshi, iminyururu iratunganijwe neza, kandi igipimo cya de-gahunda kiri hejuru y'icyateganijwe [72], bikagabanya imbaraga za filime, bikaviramo imbaraga za kanseri ya HPMC. Kubera ko ingaruka zikaba zishyuwe nimbaraga za kanseri ya firime ya HPMC, umubare wa glycerol ntugomba kuba mwinshi.

Nkuko bigaragara ku gishushanyo 3.3 (B), hiyongereyeho inyongeramuti Iyo ingano ya sorbinool yari 0.15%, kwihirika kuri firime ya HPMC yageze kuri 45%, hanyuma kurera firime buhoro buhoro yagabanutse buhoro buhoro. Imbaraga za kanseri ziragabanuka vuba, hanyuma zihindagurika hafi ya 50mp hamwe no kongeramo indwara yonoliya. Birashobora kugaragara ko mugihe ingano ya sorbito yongeyeho ni 0.15%, ingaruka za plastiki ni nziza. Ni ukubera ko hiyongereyeho molekile ntoya ya Sorbinool igabanya gahunda isanzwe yiminyururu ya molekile, ikora ikinyuranyo hagati ya molekile nini, kandi imbaraga ziroroshye, kandi imbaraga zigenda ziyongera kuri firime yiyongera kandi imbaraga za tensile zigabanuka. Nkuko iryisi ya sorbittiol yakomeje kwiyongera, kwihitiramo film byagabanutse, kuko molekile ntoya ya marronolecules, bikaviramo kugabanya buhoro buhoro ingingo za Makanglecules no kugabanuka kwa Filime.

Kugereranya ingaruka za plastiki ya glycerol na sorbinol kuri firime za HPMC, ongeraho 0.15% glycerol birashobora kongera kurambura mukiruhuko cya firime kugeza kuri 50%; Mugihe wongeyeho 0.15% sorbinool irashobora kongera umwanya gusa kuruhuka ka firime igipimo kigera kuri 45%. Imbaraga za tensitile zaragabanutse, kandi kugabanuka kwari nto igihe Glycerol yongeyeho. Birashobora kugaragara ko ingaruka zishushanyije za Glycerol kuri firime ya HPMC iruta izo nyarurima.

3.3.4 Ingaruka za Glycerol na Sorbinol kumurongo wa optique ya firime ya HPMC

(a) glycerol (b) Sorbinol

Igishushanyo3

Umucyo woherejwe na Haze nibyingenzi byingenzi byumurisho wa firime yapakira. Kugaragara no gusobanuka ibicuruzwa byapakiwe cyane biterwa no kwanduza urumuri no gukurura firime yo gupakira. Nkuko bigaragara ku gishushanyo 3.4, hiyongereyeho Glycerol na Sorbinol bombi bagize ingaruka kumiterere ya optique ya firime ya HPMC, cyane cyane igihu. Igicapo 3.4 (a) ni igishushanyo cyerekana ingaruka za glycerol yongeyeho kumitungo ya optique ya firime ya HPMC. Hamwe na Glycerol, kohereza firime ya HPMC byiyongereye bwa mbere hanyuma bigagabanuka, kugera ku gaciro ntarengwa hafi 0.25%; Umuhondo wiyongereye vuba hanyuma buhoro. Irashobora kugaragara mu isesengura ryavuzwe haruguru mugihe umubare wo kwiyongera wa Glycerol ari 0.25%, imiterere ya optique ya firime nibyiza, bityo rero kwiyongera kwa Glycerol ntigomba kurenga 0.25%. Igishushanyo 3.4 (b) Ese igishushanyo cyerekana ingaruka za sorbitli yongeyeho kumitungo ya optique ya firime ya HPMC. Birashobora kugaragara uhereye ku ishusho ko hiyongereyeho sokoli, haraga igabanuka rya mbere, hanyuma iragabanuka buhoro hanyuma ziyongera, kandi koherezwa kwa mbere hanyuma biriyongera. Yagabanutse, kandi umucyo woherejwe na Haze wagaragaye nimboro icyarimwe mugihe umubare wa Sorbittol wari 0.45%. Birashobora kugaragara ko mugihe umubare wa Sorbito wongeyeho uri hagati ya 0.35 na 0.45%, imitungo yayo ya optique nibyiza. Kugereranya ingaruka za glycerol na sorbinot kumitungo ya optique ya firime ya HPMC, irashobora kugaragara ko Sorbitton idafite ingaruka nke kumitungo ya optique ya firime.

Muri rusange, ibikoresho hamwe no kwanduza urumuri rwinshi bizagira igihu gito, naho ubundi, ariko ntabwo buri gihe aribyo. Ibikoresho bimwe bifite imyanya minini ariko nanone hari indangagaciro ndende, nka firime zoroheje nkikirahure gikonje [73]. Filime yateguwe muri iyi kigeragezo irashobora guhitamo plastisticer ikwiye kandi yiyongera umubare ukurikije ibikenewe.

3.3.5 Ingaruka za Glycerol na Sorbinol kumazi yoroheje ya firime ya HPMC

(a) glycerol (b) Sorbinol

Igishushanyo

Igishushanyo 3.5 cyerekana ingaruka za glycerol na sorbinol kumazi yoroheje ya firime ya HPMC. Birashobora kugaragara uhereye ku ishusho ko hamwe no kwiyongera kw'ibice bya plastikisi, igihe cyo kunyerera cy'amazi cya firime ya HPMC iraragabanuka buhoro buhoro, kandi Glycerol yigira ingaruka zikomeye ku bushake bwamazi ya firime ya HPMC kuruta sorbito. Impamvu yatumye hydroxypropyl methylcellse ifite amazi meza ni ukubera ko hariho umubare munini wamatsinda ya hydroxyl muri molekile yayo. Duhereye ku isesengura ry'ibikoresho bya infrared, birashobora kugaragara ko hiyongereyeho urujya n'uruza rw'imikino ya HPMC muri Molekile ya HPMC igabanuka, bityo umubare w'amatsinda ya hydhilex.

3.4 Ibice by'iki gice

Binyuze mu isesengura ryavuzwe haruguru rya firime za HPMC, birashobora kugaragara ko Slyceroders Glycerol na Sorbitton biteza imbere imitungo ya HPMC kandi byongera kurambura film. Igihe cyongeyeho Glycerol ni 0.15%, imitungo ya mashini ya firime ya HPMC ni nziza, imbaraga za kanseri ni hafi 60MPA, no kwirangira, no kurera birenga 50%; Iyo kwiyongera kwa Glycerol ni 0.25%, imiterere ya optique nibyiza. Iyo ibikubiye muri sorbittool ari 0.15%, imbaraga za kanseri ya firime ya HPMC igera kuri 55mpa, kandi kurera ikiruhuko byiyongera kuri 45%. Iyo ibikubiye muri sorbittool ari 0.45%, imiterere ya optique ya firime nibyiza. Byombi byaciwe byamazi yoroheje ya firime ya HPMC, mugihe sorbitdol yagira ingaruka nke kumazi menshi ya firime ya HPMC. Kugereranya ingaruka za plastistizers ebyiri kumiterere ya firime ya HPMC yerekana ko ingaruka za Plastique ya Glycerol kuri firime za HPMC ziruta iz'imirima.

UMUTWE WA 4 Ingaruka zo Kwirukana Ibikorwa Kuri HPMC Amazi Yapakiwe Amazi

4.1 Intangiriro

HydroxyPropyl methylcellse ikubiyemo amatsinda menshi ya hydroxyl hamwe namatsinda ya hydroxyPropoplexy, niko bifite amazi meza. Uru rupapuro rukoresha amazi meza yo kwitegura igitabo cyicyatsi kibisi no guhinga ibidukikije. Ukurikije porogaramu ya firime yo gukosora amazi, gusenya byihuse bya firime yo gukosora amazi birasabwa muri porogaramu nyinshi, ariko rimwe na rimwe byatinze gusenya nabyo bifuzwa [21].

Kubwibyo, muri iki gice, Gltaraldehyde akoreshwa nkumukozi wahinduwe kuri firime yo gupakira amazi ya hydroxypropyl methylcellelll methylcellse kugirango ugabanye film kandi ukemure igihe cyo kwishyuza amazi. Ingaruka za Gltaraldehyde ingano yinyongera ku mazi yonyine, umutungo wa mashini na optique imiterere ya firime za hydroxypropyl methylcellse byize cyane.

4.2 Igice cyageragejwe

4.2.1 Ibikoresho byubushakashatsi nibikoresho

Imbonerahamwe 4.1 Ibikoresho byubushakashatsi hamwe nibisobanuro

4.2.2 Gutegura amanota

1) gupima: Gupima umubare runaka wa hydroxyproppopyl methylcellse (5%) hamwe na elegitoroniki;

2) guseswa: Iseswa rya HydroxyPropyl Methylcellellse yongewe mu mazi yateguwe, akingurwaga n'ubushyuhe bw'icyumba ndetse no ku ya 0.25%, hanyuma akingamira igihe runaka (defoamoing), hamwe n'amazi ahinnye Hamwe na GlUtAralddehyde yongeyeho;

3) Gukora firime: Gutera filime ikora amazi mubirahure kandi bigatera agasanduku kwumirwa kuri 40 ~ 50 ° kuzimya film, hanyuma ubishyire mumasanduku yumisha.

4.2.3 Kuranga no Kwipimisha Imikorere

4.2.3.1 Infrared yinjije (FT-IR)

Gukuramo infraft ya firime ya HPMC yagennye gukoresha Nicolet 5700 yagereranijwe yagenwe na sosiyete y'Abanyamerika ya hafi na Spectrum.

4.2.3.2 Yamazaki X-ray itandukanye (Xrd) gusesengura

Mugari-inguni x-ray itandukanye (xrd) ni isesengura ryamateka yimiterere yikintu kurwego rwa molekile. Muri iyi mpapuro, imiterere ya videwo ya firime yoroheje yagenwe hakoreshejwe arl / Xtra X-Ray itandukanye na Thermo Arl yo mu Busuwisi. Ibipimo byo gupima: Inkomoko ya X-Ray ni umukandara wa nikel cu-kα (40 kv, 40 MA). Scan inguni kuva 0 ° kugeza 80 ° (2θ). Scan Umuvuduko 6 ° / Min.

4.2.3.3 Kwiyemeza kwikebagura amazi: kimwe na 2.2.3.4

4.2.3.4 Kwiyegurira imitungo

Ukoresheje instron (5943) Miniature Electronic Imashini ya Tensile Yigenga ya Intern (SHAnghai) Ibizamini byo gupima Filiziya, ikizamini cya metero 50, hitamo urugero rw'imigezi ndetse n'ubutaka busukuye.

4.2.3.5 Kwemeza imiterere ya optique

Ukoresheje umucyo wa transmitminance Haze Ikizamini, hitamo icyitegererezo cyo kugeragezwa nubuso butanduye kandi nta mucyo wa radim, hanyuma upime urumuri rwa radim hamwe na filime ku bushyuhe bwicyumba (25 ° C na 50% RH).

4.2.4 Gutunganya amakuru

Amakuru yubushakashatsi yatunganijwe na Excel afata software yinkomoko.

4.3 Ibisubizo n'ibiganiro

4.3.

Igishushanyo 4.1 ft-ir ya firime ya HPMC munsi ya Gltaraldehyde

Kugereranya kwanga hakoreshejwe uburyo bukomeye bwo kuranga amatsinda yimikorere akubiye mumiterere ya molekeland no kumenya amatsinda yimikorere. Kugirango usobanukirwe no kurushaho guhindura imiterere ya hydroxypropyl methylcellse nyuma yo guhinduranya, ibizamini bya infrad byakorewe kuri firime ya HPMC mbere na nyuma yo guhindura. Igishushanyo 4.1 cyerekana ko inzego za Filime za HPMC zifite umubare munini wa glutaraldehyde, hamwe no guhindura firime za HPMC

Impinga yinjira muri Vibrational ya -Oh iri hafi ya 3418cm-1 na 1657cm-1. Kugereranya na SPRACKERED NA SPRACK ya firime za HPMC, irashobora kugaragara ko hiyongereyeho-3418cm-1 Molekile yagabanutse, yatewe no guhuza imiti hagati ya hydroxyl ya hpmc na diadehde itsinda rya diadiddehyde [74]. Byongeye kandi, wasangaga kongeweho Gltaraldehyde ntabwo yahinduye umwanya wa buri kintu gifatika cya HPMC, cyerekana ko hiyongereyeho gltaraldehyde ntabwo yasenya amatsinda ya HPMC ubwayo.

4.3.2

Mugukora x-ray biratandukanye kubikoresho no gusesengura uburyo butandukanye, nuburyo bwubushakashatsi bwo kubona amakuru nkimiterere cyangwa morphologiya ya atome cyangwa molekile imbere yibikoresho. Igishushanyo 4.2 cyerekana imiterere ya Xrd ya firime ya HPMC hamwe na Gltaraldehyde itandukanye. Hamwe no kwiyongera kwa Gltaraldehyde, ubukana bwurugero rwa HPMC hafi 9.5 ° na 20.4 ° gucika intege, kuko aldehhdes kuri molekile yagabanutse. Guhuza resed bibaho hagati yitsinda rya hydroxyl hamwe nitsinda rya hydroxyl kuri molekile ya HPMC, ituma urujya n'uruza rw'umugambi wa molecular [75], bityo tukagabanya ubushobozi bwa gahunda ya molekile ya HPMC.

Igishushanyo cya 4.2 xrd ya firime ya HPMC munsi ya Gltaraldehyde

4.3.3 Ingaruka za GlUТsitani kumuntu woroheje kuri firime za HPMC

Igishusho

Kuva ku gishushanyo cya 4.3 Ingaruka za Gltaraldehyde yongeyeho kumazi yoroheje ya firime ya HPMC, birashobora kugaragara ko hamwe na glutaraldehyde igipimo cya firime ya HPMC ndende. Umusaraba uhungabana bibaho hamwe nitsinda rya Altehyde kuri gltaraldehyde, bikaviramo kugabanuka kwi matsinda ya hydroxyl muri mol ya hpmc muri firime ya HPMC no kugabanya ibicuruzwa byonyine bya firime ya HPMC.

4.3.4 Ingaruka za Gltaraldehyde kubintu bya mashini ya firime ya HPMC

Igishushanyo

Kugirango dukore iperereza ku ngaruka za Gltaraldehyde ku miterere ya mashini ya firime ya HPMC, imbaraga za kanseri no kwihitiramo ibintu byahinduwe byageragejwe. Kurugero, 4.4 nigishushanyo cyingaruka za gltaraldehyde inzitira imbaraga za tensile no kwihitiramo film. Hamwe no kwiyongera kwa Gltaraldehyde, imbaraga za kanseri no kurambura firime ya HPMC yiyongereye mbere hanyuma agabanwa. icyerekezo cya. Kuva yahuje glUtAralddehyde na selile ni iy'ubuzima buhuza, nyuma yo kongeramo Glutaraldehyde molekile hamwe na molekile yo guhuza Filime. Hamwe no kwiyongera kwa GlUtAralddehyde, kugabanya ubucucike mubisubizo byiyongera, bigabanya umuvandimwe kuri molekile, kandi ibice bya moleki ntibigaragara byoroshye mubikorwa byingufu za HPMC bigabanya macroscopique [76]. Kuva ku gishushanyo 4.4, ingaruka za gltaraldehyde kumitungo ya mashini ya firime ya HPMC yerekana ko mugihe wongeyeho Glutaraldehyde ari 0.25%, ingaruka zidasanzwe za firime za HPMC nibyiza.

4.3.5 Ingaruka za Gltaraldehyde kumitungo ya optique ya firime ya HPMC

Umucyo woherejwe na Haze ni bibiri byingenzi byingenzi bya optique ibipimo bya firime zo gupakira. Inzitiro nini, ni byiza gukorera mu mucyo wa firime; Umugozi, uzwi kandi ku nkombe, yerekana urugero rw'amahanga ya firime, kandi urunini rwa Haze, rurushijeho kuba bibi kuri film. Igicapo 4.5 ni umurongo uhinduranya wongeyeho gltaraldehyde ku miterere ya optique ya firime ya HPMC. Birashobora kugaragara uhereye ku ishusho ko hamwe no kongeraho kwiyongera kwa GlUtmince Haze bwa mbere kugabanuka hanyuma ukayongera. Iyo kongeramo GlUtAraldHehyde yari 0.25%, kohereza firime ya HPMC byageze ku gaciro ntarengwa cya 93%, kandi igihu cya kigeze agaciro ntarengwa cya 13%. Muri iki gihe, imikorere ya optique yari nziza. Impamvu yo kwiyongera mubintu bya optique ni uguhuza kwambukiranya gltaraldehyde molekile na hydroxypropyl methylcellse, hamwe nuburyo bworoshye kandi bwiyongereyeho film ya HPMC [77-79]. Iyo umukozi uhuza akarengane cyane, aho bahuriramo ibice byambukiranya, ugereranije na molekile ya sisitemu biragoye, kandi pel phenomenon biroroshye kubaho. Kubwibyo, imitungo ya optique ya firime ya HPMC iragabanuka [80].

Igishushanyo

4.4 Ibice by'iki gice

Binyuze mu isesengura ryavuzwe haruguru, imyanzuro ikurikira irashushanywa:

1) Imyitozo ya Infrared ya Gltaraldehyde-Crossil Film Crossm yerekana ko film ya GlUtAraldehyde na HPMC igira ingaruka zihuza.

2) Birakwiye kongeraho glutaraldehyde murwego rwa 0.25% kuri 0.44%. Iyo kwiyongera kwa Glutaraldehyde ari 0.25%, imiterere yuzuye yubufatanye nantungamubiri za firime ya HPMC nibyiza; Nyuma yo guhuza abantu, amazi yo kwikeba ya firime ya HPMC irambuye kandi ibicuruzwa byonyine byagabanutse. Iyo kwiyongera kwa GlUtAralddehyde ni 0.44%, igihe cyo kwishyuza amazi kugera kuri 135min.

UMUTWE WA 5 Antioxidant HPMC Amazi Yapakiwe Amazi Yapakurura

5.1 Intangiriro

Kugirango wagure porogaramu ya HydroxyPropyl Methylcellse film mu gupakira ibiryo, iki gice gikoresha Antioxident AntioxIdent, kandi ikoresha igisubizo cyo guteranya film (AOB) nka Antioxydant yo Gukoresha Filime yo Gukoresha Filime Gutegura Antiofsidants hamwe nibice byinshi. Antioxidant HPMC y'amazi ya siporo, wige ibintu bya Antioxident, kwishura amazi, umutungo wa mashini na kamera kamazi ya firime, hanyuma utange urufatiro rwo gusaba sisitemu yo gupakira ibiryo.

5.2 Igice cyageragejwe

5.2.1 Ibikoresho byubushakashatsi nibikoresho byo kugerageza

Tab.5.1 Ibikoresho byubushakashatsi hamwe nibisobanuro

Tab.2.2 Ibikoresho byubushakashatsi nibisobanuro

5.2.2 Gutegura amanota

Tegura HydroxyPropyl methylcellse Film Yapakiwe Amazi Antiof antiof antiofyl Methylcelll Methylcellel Methylcellus Mething Mething Igisubizo cya Methylcellus (0%%, 0.03%, 0.05%, 0.05%, 0.05%, 0.05%, 0.09%) ya Antiof Leaf Antioxidents kuri Filime ya Cellulose, kandi ukomeze kubyutsa

Kugira ngo uvanze byuzuye, reka uhagarare mucyumba cyicyumba cyiminota 3-5 (defoaming) kugirango utegure ibisubizo bya HPMC birimo ibisubizo bitandukanye bya firime bitandukanye byimigano antiof antioflidants. Kuma muburyo bwo guturikamo, hanyuma ubishyire mu kigero cyumye kugirango ukoreshe nyuma ukuramo film. Amababi ya hydroxppepoyl methylcellsel Methoycellse-firime yo gupakira amazi yongeyeho hamwe namababi yimigano yitwa AntioxIdent nka firime ya AOB / HPMC muri make film.

5.2.3 Kuranga no Kwipimisha Imikorere

5.2.3

Spectra ya infrared ya firime ya HPMC yapimwe muburyo bwa ATR ikoresheje nicolet 5700 iyobowe na enterineti ya enterineti yakozwe na thermoelectric.

5.2.3.2 Angle X-ray itandukanye (Xrd) gupima: kimwe na 2.2.3.1

5.2.3.3 Kugena Umutungo wa Antioxident

Kugirango upime imitungo ya Antioxident ya firime ya HPMC yateguwe na AOB / HPMC uburyo bwo guhagarika umutima bwakoreshejwe muri iyi kigeragezo kuri DPPH kubuntu, kugirango upime rushya kuri DPEDS.

Gutegura igisubizo cya DPPH: Muburyo bwo guswera, gushonga 2 ya DPP ya DPPH muri 40 ML ya Ethanol Solvent, na Sonicate kuminota 5 kugirango ukore umwambaro 5 kugirango ugire umwambaro. Ububiko muri firigo (4 ° C) kugirango ukoreshe nyuma.

Kuvuga uburyo bwo kugerageza bwa Zhong Yuansheng [81], hamwe no guhindura gato, gupima AFORY AMAZI YO GUTANGA NO GUKORA, hanyuma ugereranye na ml ya DPPH. ni a0. Gupima agaciro: Ongeramo ML ya DPPH igisubizo cyikizamini, hanyuma ongeraho ML ya ML ya HPMC yo kuvanga neza, gupima agaciro hamwe na UV igenzura ryuzuye, hamwe namazi asabwa kuri buri tsinda. DPPH Ubuntu Ubucuruzi bwo Kubara Kubara Yerekeza kuri formula ikurikira,

Muri formula: A ni ukuvuga icyitegererezo; A0 nubugenzuzi bukabije

5.2.3.4 Kwiyegurira imitungo: kimwe na 2.2.3.2

5.2.3.5 Kwemeza imiterere ya optique

Ibintu bya optique nibipimo byingenzi bya transparency film yapakiye, cyane cyane harimo no kwanduza no gukurura film. Gufata no gushora inyamu byapimwe ukoresheje testers ya trance. Umucyo wohererezanya kandi haze firime ya firime (25 ° C na 50% RH) ku cyitegererezo cy'ibizamini gifite ubuso busukuye kandi nta mucyo.

5.2.3.6 Kwiyegurira Amazi Kudakemurwa

Kata 30mm × 30mm film ifite ubunini bugera kuri 45μm, ongeraho 100ml y'amazi, shyiramo film hagati yamazi akomeye, hanyuma upime igihe cya firime kizimira burundu. Niba firime ifatanye nurukuta rwa beaker, igomba kongera gupimwa, kandi ibisubizo bifatwa nkikigereranyo cyiminsi 3, igice ni min.

5.2.4 Gutunganya amakuru

Amakuru yubushakashatsi yatunganijwe na Excel afata software yinkomoko.

5.3 Ibisubizo n'Isesengura

5.3.1 Isesengura rya FT-IR

Ishusho 15.1 ftir ya HPMC na AOB / HPMC Filime

Muri molekile kama, atome ikora ubumwe bwimiti cyangwa amatsinda yimikorere ari muburyo bwo guhora kunyeganyega. Iyo molekile kama ikaranze itangwa numucyo wa infrad, imiti yimiti cyangwa amatsinda yimikorere muri molekile arashobora gukuramo kunyeganyega, kugirango amakuru ajyanye no kwivuza cyangwa amatsinda yimikorere muri molekile arashobora kuboneka. Igicapo 5.1 cyerekana FTIR SPIR ya firime ya HPMC na AOB / HPMC. Kuva ku gishushanyo cya 5, birashobora kugaragara ko urujijo ruranga hydroxyproppopyl methylcellse ahanini yibanda cyane muri 2600 ~ 3700 cm-1 na 750 ~ 1750 ~ 1750 ~ 1750. Inkunga ikomeye yo kunyeganyega muri CM 950-1250 ni akarere karanga karangwa na Co Skeleton irambuye. Itsinda ryinjira muri firime ya HPMC hafi ya 3418 CM-1 iterwa no kunyerera kwa Oh Bond, hamwe nitsinda rya hydroxyle, kandi ryinshi ryitsinda rya hydroxyle kuri 1657 ryatewe no kuzura urwego [82]. Impinga yuzuye kuri 1454cm-1, 1373cm-1, 1315CM-1 na 945cm-1 zari zinyeganyega, mu indege no mu ndege no hanze y'indege iri kunyeganyega muri -CH3 [83]. HPMC yahinduwe na AOB. Hiyongereyeho Aob, umwanya wa buri kintu kiranga AOB / HPMC ntabwo cyahindutse, byerekana ko kongeramo Aob atatsembye amatsinda ya HPMC ubwayo. Kurambura hejuru ya Oh Bond mu itsinda ryinjira muri firime ya AOB / HPMC hafi ya 3418. 12], irashobora kuboneka ko kongeramo AOB igira ingaruka kumitekerereze ya hydrogen.

5.3.2 Xrd isesengura

Igishushanyo cya 15.2 xrd ya HPMC na AOB /

Igishushanyo cya 15.2 Xrd ya HPMC na AOB / HPMC Filime

Imiterere ya sitstaline ya firime yasesenguwe na gato-angle X-ray itandukanye. Igishushanyo 5.2 cyerekana imiterere ya Xrd ya firime ya HPMC na AAOB / HPMC Film. Irashobora kugaragara ku ishusho ivuga ko filime ya HPMC ifite impinga 2 itandukanye (9.5 °, 20.4 °). Hiyongereyeho Aob, impinga itandukanye nka 9.5 ° na 20.4 ° yacitse intege cyane, yerekana ko molekile ya firime ya AOB / HPMC itunganijwe muburyo butondetse. Ubushobozi bwaragabanutse, bwerekana ko kongeramo gahunda ya HydroxyProppeporl Methylcelliulose urunigi rwa molekile, kandi agabanya gahunda isanzwe ya molekile, methylcellropyl methylcellse.

5.3.3 Umutungo wa Antioxident

Kugirango usuzume ingaruka za aob zitandukanye zo kurwanya elms ya aob / hpmc, filime zitandukanye za AOB (0,13%, 0.03%, 0.09%). Ingaruka z'igipimo cy'urufatiro rw'ifatizo, ibisubizo byerekanwe ku gishushanyo 5.3.

Ishusho

Irashobora kugaragara kuva ku gishushanyo 5.3 kongeweho aoo antioxidant yatezimbere cyane igipimo cya FPCH cyateye imbere, kandi, imitungo ya DPOXID inoze, yiyongera bwa mbere, buhoro buhoro, buhoro buhoro yiyongereyeho buhoro buhoro. Iyo kwiyongera kwa AOB ari 0,03%, firime ya AOB / HPMC ifite ingaruka nziza ku gipimo cya DPPH kigera kuri 89.34%, ni ukuvuga firime ya AOB / HPMC ifite imikorere myiza yo kurwanya oki-oki-oki-oki-oki Iyo aob ibirimo bya 0.05% na 0.07%, DPPH Fliedical Spedical Cleveding Falef ya aob / HPMC ya firime kurenza iya 0.01% kurenza iyitsinda rya 0.03%; Ibi birashobora guterwa antioxixidexday karemano yiyongera kwa AOB yayoboye agglomeration ya molekile ya aob molekile, bityo igabura ingaruka za firime ya AOB / HPMC. Birashobora kugaragara ko firime ya AOB / HPMC yateguwe mubushakashatsi ifite imikorere myiza yo kurwanya oki-okiside. Igihe umubare wo kwiyongera ni 0.03%, imikorere yo kurwanya oki-oki-oki-hpmc niyo ikomeye.

5.3.4 Amazi Kudakemurwa

Kuva ku gishushanyo 5.4, ingaruka za Antiof Leaf Antiofdidents Kukecururizwa ryamazi ya Flowroxpropyl Methylcellropyl Methylcellrose Films, birashobora kugaragara ko Athylcellroppeppoulose Films, irashobora kugaragara ko Athylcellroproplese Film za Methity Nyuma yo kongeramo AOB, hamwe no kongera umubare wa AOB, igihe cyo gukemura amazi cya firime cyari kigufi, cyerekana ko amazi-yakemuwe ya firime ya AOB / HPMC yari nziza. Nukuvuga, hiyongereyeho AOB itezimbere AOB / HPMC yamasoko yamazi ya firime. Duhereye ku isesengura rya Xrd isesengura, birashobora kugaragara ko nyuma yo kongeramo AOB, kristu ya firime ya AOB / yoroshye, kandi imbaraga za firime za AOB / HPM / HOB / HPM / HPM / HPM / HPMC Kukegura amazi ya film.

Igishushanyo

5.3.5 Imashini

Ishusho

Gusaba ibikoresho bya firime bitoroshye kandi byinshi, kandi imitungo yacyo ifite uruhare runini kumyitwarire ya serivisi ya sisitemu ishingiye kuri serivisi ya Membrane, yabaye ahantu h'ubushakashatsi bukomeye. Igicapo 5.5 cyerekana imbaraga za tensile no kwihitiramo imirongo ya aob / hpmc films. Birashobora kugaragara uhereye ku gishushanyo kijyanye na aob zitandukanye zifite ingaruka zikomeye kumiterere ya mashini ya firime. Nyuma yo kongeraho AOB, hamwe no kwiyongera kwa AOB, AOB / HPMC. Imbaraga za kanseri ya firime zerekanye inzira yamanutse, mugihe kwihitiramo mukiruhuko byerekanaga ubwikunde bwa mbere hanyuma bigagabanuka. Iyo aob ibirimo ari 0.01%, kwihirika ku biruhuko bya firime byageze ku gaciro ntarengwa ka 45%. Ingaruka za AOB kumurongo wa mashini ya firime ya HPMC iragaragara. Kuva musesengura rya XDD, birashobora kugaragara ko hiyongereyeho Antioxidant AOB igabanya inyamanswa ya AOB / HPMC, bityo ikagabanya imbaraga za kanseri ya firime ya AOB / HPMC. Kurangiza kuruhuka bwa mbere hanyuma bigabanuka, kuko AOB ifite amazi meza no guhuza, kandi ni ibintu bito bya molekile. Mugihe cyo guhuza na HPMC, imbaraga zimikoranire hagati ya molekile ziracika intege kandi film yoroha. Imiterere ikomeye ituma firime ya AOB / HPMC yoroshye kandi hejuru kubiruhuko byiyongera; Nkuko AOB ikomeje kwiyongera, kwihitiramo film ya AOB / HPMC iragabanuka, kandi nta moti yoroshye yo kwiyongera mugihe cyambere cya macromolecules, bityo film ihangayitse, kugirango uburebure bwa firime ya AOB / HPMC igabanuka.

5.3.6 Ibintu byiza

Igishushanyo

Igishushanyo 5.6 ni igishushanyo cyerekana impinduka mu kwanduza no gukurura firime ya AOB / HPMC. Birashobora kugaragara uhereye ku ishusho ko hamwe no kongera umubare wa aob wongeyeho, kohereza filime ya AOB / HPMC bigabanuka kandi haza kwiyongera. Iyo aob irenze 0.05%, igipimo cyo guhindura cyo kwanduza no gukurura firime ya aob / HPMC byatinze; Iyo aob imaze kurenga 0.05%, igipimo cyahinduwe cyo kwanduza kandi kirangiye. Kubwibyo, ingano ya aob yongeyeho ntigomba kurenga 0.05%.

5.4 Ibice by'iki gice

Gufata imigano ya BambooxyIdant (AOB) nka AntioxyPropyl Methylcellus (HPMC) nka matrix isanzwe ya fagitire, ubwoko bushya bwo gupakira antioxident nigisubizo cyo gukora film. Filime yo gupakira amazi ya Aob / HPMC yateguwe muri iyi ubushakashatsi bufite imiterere yimikorere yo kurwanya oki-okiside. Filime ya AOB / HPMC hamwe na 0.03% ABO ifite igipimo cya 89% kuri DPPH Flicals, hamwe nuburyo bwiza, burenze ibyo nta AB. Filime ya HPMC kuri 61% iratera imbere. Gukemura amazi nabyo byateye imbere cyane, kandi imitungo na optique biratangira. Kurwanya okiside itezimbere ibikoresho bya firime ya AOB / HPMC byaguye gukoreshwa mubipfunyika ibiryo.

UMUTWE WA KI UMWANZURO

1) Hamwe no kwiyongera kw'imikino ya HPMC yo gukemura, imitungo ya mashini ya firime yabanje kwiyongera bwa mbere hanyuma ikagabanuka. Iyo film ya HPMC yerekanaga 5%, ibintu bya mashini ya firime ya HPMC byari byiza, kandi imbaraga za kanseri zari 116MPA. Kurambura mukiruhuko ni 31%; imiterere ya optique n'amazi yo kugabana amazi.

2) Hamwe no kwiyongera kwa firime ikora ubushyuhe, imiterere ya mashini ya firime zabanje kwiyongera kwa mbere hanyuma igabanuka, imitungo ya optique iratera imbere, kandi kudutera amazi yagabanutse. Iyo ubushyuhe bwo gukora firime ari 50 ° C, Ibikorwa rusange nibyiza, imbaraga za terefone ni 110%, kandi igihe cyangiza amazi ni hafi ya saa kumi n'ebyiri za mugitondo.

3) Ukoresheje plasticers kugirango unoze ubukaze bwa firime ya HPMC, hiyongereyeho uruganda rwa Glycerol, kwihitiramo ibiruhuko bya firime ya HPMC byiyongereye cyane, mugihe imbaraga za kanseri zaragabanutse. Iyo ingano ya Glycerol yongeyeho yari hagati ya 0.15% na 0.25%, kwihitiramo firime ya HPMC byari hafi ya 50%, kandi imbaraga za kanseri zari hafi ya 60MPA.

4) Hamwe na Sokbinool, kwihitiramo kubicana bya firime biyongera hanyuma bigagabanuka. Iyo kongeramo amarbittool ari hafi 0.15%, kwihirika ku kiruhuko bigera kuri 45% n'imbaraga za tensile ni 55mpa.

5) Byongeye kandi, inyoni ebyiri, glycerol na sorbinot, byombi byagabanije imitungo ya optique n'amazi ya firime ya HPMC, kandi kugabanuka ntibyari byiza. Kugereranya ingaruka zishushanyije za plastistie ebyiri kuri firime za HPMC, urashobora kugaragara ko ingaruka zishushanyije za Glycerol ziruta izo nyarurima.

6) Binyuze mu buryo bukennye (FTER) n'inyeshyamba z'ubugari x-ray isesengura rya glUtAraldehyde na hpmc na kristu na kristu nyuma yo kwirukanwa. Hiyongereyeho umukozi wambukiranya umushyitsi, imbaraga za kansedi hamwe no kurambura firime za HPMC zateguwe bwa mbere zabanje kwiyongera kwa mbere hanyuma ziragabanuka. Iyo kongeramo gltaraldehyde ari 0.25%, imiterere yuzuye ya firime ya HPMC nibyiza; Nyuma yo guhuza abantu, igihe cyo kwishyurwa amazi kirambuye, kandi kwikebagura amazi bigabanuka. Iyo kongeramo glutaraldehyde ari 0.44%, igihe cyo gusanga amazi kigera kuri 135min.

7) Ongeraho umubare ukwiye wa AOB Antioxydidant kuri Film-Gukora Filime ya Filime ya HPMC, yateguye AOB / HPMC y'amazi yo gupakira amazi afite imitungo yimikorere ya anti-oki-oki-okiside. Filime ya AOB / HPMC hamwe na 0.03% AOB yongeyeho 0.03% Aob Kuri Scavenger Spedical igipimo cya 89%. Gukemura amazi nabyo byateye imbere cyane, kandi imitungo na optique biratangira. Iyo umubare wongeyeho 0.03% ABob, ingaruka zo kurwanya ibyari byiza, kandi kuzamura imikorere yo kurwanya oub / hpmc yagura porogaramu yibikoresho bya firime mubikoresho byo gupakira.