Nigute hpmc ikoreshwa mubyoherejwe?

HydroxyPropyl MethylcellllAlose (HPMC) ni polymedi kandi ikoreshwa cyane mu nganda zitandukanye, cyane cyane mu mata. Ikora intego nyinshi kubera imitungo yihariye, irimo ubushobozi bwo gukora firime, kubyimba, guteranya, no gukomera ibintu.

1. Kumenyekanisha HPMC
HydroxyPropyl Methylcellsellse (HPMC) ni umuvuduko wa fililose yahinduwe, yakomokaga kuri selile karemano inyura mu ruhererekane rw'imyitwarire minini irimo amatsinda ya Methyl na hydroxyPropyle. Urwego rwo gusimbuza nuburemere bwa molekile ya HPMC igena imitungo yacyo hamwe nibisabwa muburyo butandukanye. Mu mari ya HPMC ahabwa agaciro kukesha mu mazi, kamere itari ishinga, biocompasogisi, n'ibidukikije.

2. Inshingano za HPMC mumatwi
HPMC irashobora gukora muruhare rwinshi rwingenzi muburyo bwo gutwikira:

2.1. Gushiraho firime
Imwe mu nshingano z'ibanze za HPMC muri coatings ni nk'umukozi ushinzwe film. Iyo gushonga mumazi cyangwa ibindi bicuruzwa, HPMC irashobora gukora film hamwe na fluxible iyo yumutse. Ubu bushobozi bwo gukora film ningirakamaro mubice bitandukanye, nkibi bikoreshwa muri farumasi (urugero, amatara ya tablet), ibicuruzwa byibiribwa, hamwe nibikorwa byinganda. Filime itanga inzitizi ikingira ishobora kugenzura ubuhehere, kunoza isura, no kuzamura kuramba.

2.2. Umukozi wijimye
HPMC ikoreshwa cyane nkumukozi wijimye mubikota. Ubushobozi bwayo bwo kongera viscosity nibyiza byo kubungabunga imitungo yifuzwa yifuzwa. Uyu mutungo wemeza ko igikombe gishobora gukoreshwa neza kandi neza, nta gutonyanga cyangwa kugaburira. Ingaruka zijimye za HPMC ni ingenzi cyane mumavuta ashingiye ku mazi, aho bifasha guhagarika amacakubiri ya pigmesi n'abashubije.

2.3. Kumarana no gukandamiza
Mu bice, cyane cyane izifite amazi, HPMC ikora nka Emulsifier na Stabilizer. Ifasha mugushinga no guhogereza Amagana mugabanya amakimbirane yubuso hagati yicyiciro gitandukanye (urugero, amavuta n'amazi). Uyu kumenyekanisha umutungo hemeza ko ibigize ku mukondo bikomeza guhunywa gato, kubuza gutandukana no gukumira gutandukana no kunoza ibicuruzwa byanyuma.

3. Gusaba muburyo butandukanye bwa coatations
HPMC ikoreshwa mubisabwa bitandukanye, buri wanjuje imitungo yihariye kugirango igere kubisubizo byifuzwa. Porogaramu zimwe zikomeye zirimo:

3.1. IHURIRO RY'UBUCURUZI
Mu nganda za farumasi, HPMC ikoreshwa cyane mugukora ibinini na capsules. Ibi bice bitanga intego nyinshi, nka:

Igenzurwa ryagenzuwe: Amavuta ashingiye kuri HPMC arashobora guhindura irekurwa rya farumasi ikora (APIS), kugirango umwirondoro urambye kandi ugenzurwa ibiyobyabwenge.
Kurinda: Amavuta arengera APIS mubidukikije nkubushuhe, umucyo, na ogisijeni, bishobora gutesha agaciro ibiyobyabwenge.
Kuryoha malking: Ihuriro rya HPMC rirashobora guhisha uburyohe bwibiyobyabwenge bimwe, kuzamura iyubahirizwa ryubahirizwa.

3.2. IHURIRO
HPMC ikoreshwa munganda zibiribwa kugirango ikore porogaramu, nko mubyasaruro bya bombo, ibicuruzwa bitetse, hamwe nunzuramubiri. Inyungu za HPMC mu mari y'ibiryo harimo:

Inzitizi yubushuhe: Ikora nka bariyeri yubushuhe, yongerera ubuzima bwibicuruzwa bwibiryo.
Inzitizi ya peteroli: Gukora HPMC birashobora gukumira kwimuka kwa peteroli, kubungabunga imiterere nuburyohe bwibiryo.
Umukozi wa Glazing: Itanga iherezo ryaka, rishimishije kuri bombo nibindi bitekerezo.

3.3. Inganda
Mu nganda Porogaramu, HPMC yinjijwe mu majyambere ya substrate zitandukanye, harimo n'ibyuma, plastiki, n'ibikoresho by'ubwubatsi. Imikorere ya HPMC muriyi coatings ni:

Gutezimbere kwizihiza: HPMC yongera imbaraga zo gusohoza kugeza asimbuye, kugirango uburinzi burambye.
Kuramba: Ubushobozi bwo gushinga film ya HPMC bugira uruhare mu kuramba no kurwanya amatara ku bintu by'ibidukikije nk'imirasire ya UV, ubuhehere, n'imiti.
Ubuso bworoshye: HPMC itezimbere ubuso bworoshye no kugaragara kw'inganda.

4. Uburyo bwihishe inyuma yimikorere ya HPMC
Imyitwarire ya HPMC mubice irashobora kwitirirwa imiterere yacyo na molecties:

4.1. Hydrophilicity na relubility
HPMC ni hydrophilic, iyemerera gushonga byoroshye mumazi no gukora neza, ibisubizo bya viscous. Uyu mutungo ni ngombwa mu nshingano zayo nkumuntu wijimye hamwe na firime. Hydrophilicity ya HPMC nayo ituma isabana nibindi bice biri mu ipfundo, nka pigmen hamwe nuzuzanya, kwemeza ko ikwirakwizwa rimwe na rimwe.

4.2. Gushiraho Gel
Iyo HPMC ibisubizo bishyushye, bahura na pelation ishingiye ku gukurikiza, gukora imiterere isa na gel. Uyu mutungo wa thermogetilation ni ingirakamaro cyane muri porogaramu aho kurekura ubushyuhe cyangwa hakenewe umutekano. Kurugero, mu iduka ryimiti, uyu mutungo urashobora gufasha kugenzura igipimo cyo kurekura ibiyobyabwenge.

4.3. Igikorwa cyo hejuru
MPMC Molekile irashobora kwimuka ku ntera y'amazi mu kirere, kugabanya impagarara z'ubutaka no gukora nk'ikirenga. Iki gikorwa cyo hejuru ningirakamaro kugirango ugabanye kandi utunganijwe neza mubitabiriye. Mugutera imbaraga elulisions, HPMC iremeza ko ipati ikomeza kuba inyangamugayo kandi itarangwamo inenge nkitandukana.

5. Inyungu zo gukoresha HPMC muri coatings
Gukoresha HPMC mubikota bitanga ibyiza byinshi:

BiocompaTubishoboka n'umutekano: HPMC ntabwo ari uburozi kandi biocompbleble, bigatuma iba ikwiranye na farumasi hamwe nibicuruzwa.
Ubucuti bw'ibidukikije: Gukomoka kuri Celeulose bishobora kongerwa, HPMC igira urugwiro kandi biodegradukwatable.
Guhinduranya: Ibintu byinshi byinshi bya HPMCCctions byemewe bituma bikoreshwa muburyo butandukanye bwo gutwikira, kuva mu nganda kugera mu nganda n'ibiryo.
Imikorere myiza: Gukora ibintu byateguwe hamwe na HPMC yerekana ibintu byatezimbere ibintu, nko kumenyekana neza, guhinduka, no kurwanya ibintu bishingiye ku bidukikije.

HydroxyPropyl Methylcellseliulose (HPMC) ifite uruhare runini mu nganda zifata ibyemezo kubera imitungo yihariye hamwe n'ubushobozi bwinshi. Yaba ikoreshwa nka firime yahoze, yigana, cyangwa stabilizer, HPMC itanga cyane kumikorere nuburyo bukora neza mubice bitandukanye mumirenge itandukanye. Ibisabwa byayo muri farumasi, ibiryo, nibikorwa byinganda bishimangira kunyuranya no gutangaza. Gukomeza iterambere no gutegura amashusho ya HPMC itangaza kurushaho kuzamura ubuziranenge nimikorere yamakota mugihe kizaza.