HydroxyPropyl Methylcellsellse (HPMC) ni amazi asanzwe akoreshwa na selile ya selile yakoreshejwe cyane mubwubatsi, imiti, ibiryo, ibiryo nibindi bice. HPMC ifite ihohoterwa rishingiye ku mazi, kubyimba, gushiraho filming, imitungo ihamye hamwe, kandi kwibanda ku gisubizo bigira ingaruka zikomeye ku ihohoterwa ry'amazi.
1. Amahame y'ibanze ya HPMC
HPMC ikora imiyoboro itatu yimiyoboro itatu binyuze mu kwizirika no guhuza umubiri hamwe hagati yiminyururu ya molekiri mugisubizo cyibitekerezo, bishobora gufata neza no kugumana ubushuhe. Isuku ryayo rigaragarira cyane mubice bikurikira:
Adsorption yumubiri: Amatsinda ya Hydroxyl kuri molekile ya HPMC irashobora gukora hydrogen ingwate, imikoranire ya molekile yamazi, kandi ikurura kandi igumana ubushuhe.
Ingaruka ya Viscosity: HPMC yongerera victoity yumuti kandi igabanya amazi y'amazi, bityo agabanuka ku guhumeka no kwinjira mumazi.
Ubushobozi bwo gukora firime: HPMC irashobora gukora firime yo kurinda imyenda imwe kugirango ihagarike umwuka wubushuhe.
2. Ingaruka zo kwibanda ku kugumana amazi ya HPMC
Gufungwa kw'amasoko imikorere ya HPMC bifitanye isano rya bugufi no kwibanda kubisubizo, kandi ingaruka zitandukanye zamazi zerekanwa muburyo butandukanye.
2.1 Intera nkeya
Kumwanya muto (mubisanzwe munsi ya 0.1%), molekile ya hpmc ntabwo ikora umuyoboro uhagije wigipimo gihagije mumazi. Nubwo hari ubushobozi bwihariye bwo kwinjizamo amazi no gukomera, kugumana amazi ni bike kubera imikoranire idakomeye. Muri iki gihe, kugumana amazi kumuti ahanini biterwa nubushobozi bwumubiri bwumubiri bwurunizo rwa molekile ubwayo.
2.2 intera yo hagati
Iyo kwibanda kuri HPMC biyongereye hagati ya 0.1% na 2%, imikoranire yimikorere yimikorere yiyongera kandi imiyoboro ihamye itatu yashizweho. Muri iki gihe, viscogity yo gukemura iriyongera cyane, itezimbere ubushobozi bwo gufata amazi no kugumana amazi. Molekile ya hpmc ikora umuyoboro wigitereko ukoresheje umubiri wambukiranya umubiri, kugabanya neza imigezi no guhumeka amazi. Kubwibyo, kugumana amazi ya HPMC byateye imbere cyane muburyo bwo kwibanda.
2.3 Intera ndende
Mubihe byinshi (mubisanzwe birenga 2%), molekile ya hpmc ikora imiterere yuzuye, nigisubizo cyerekana neza vicosity ndetse no kwegera leta ya Gel. Muri iyi leta, HPMC ishoboye gufata no kugumana ubushuhe ku buryo bushoboka bwose. Kwibanda cyane kuri HPMC byongera cyane ubushobozi bwo kugumana amazi kandi bigabanya urugero rwamazi, abikemerera kwerekana imikorere myiza muri porogaramu yo kugumana amazi menshi.
3. Gushyira mu bikorwa ibintu bifatika bya HPMC no kugumana amazi
3.1 Umwanya wubwubatsi
Muri minisiteri yubatswe, HPMC itezimbere imikorere yubwubatsi mugutezimbere kugumana amazi, kugabanya igihombo cyamazi mugihe cyubatswe, no kwagura igihe cyo gufungura. HPMC isanzwe ikoreshwa muri minisiteri mugihe cya 0.1% kuri 1.0%, urutonde ruringaniza neza kugumana amazi no kwerekana ibisabwa.
3.2 umurima wa farumasi
Mu binini bya farumasi, HPMC ikoreshwa nk'ibikoresho byarakaye kandi bihuza ibinini bizagera ku ngaruka zikomeje-kurekura ibiyobyabwenge mu kugenzura umubare w'amazi. Kwibanda kuri HPMC muri farumasi mubisanzwe biva kuri 1% kugeza 5%, bitanga ihohoterwa rikwiye kandi rihakanye kwemeza ubunyangamugayo no kurekura ibiyobyabwenge kuri tablet.
3.3 Umwanya w'ibiribwa
Mu nganda zibiribwa, HPMC ikoreshwa nkuwabyimbye kandi stilizer kugirango ateze imbere imiterere nogumana amazi. Kurugero, ongeraho HPMC kumugati urashobora kuzamura kugumana amazi noroheje yifu, mubisanzwe bihuza hagati ya 0.2% na 1%.
4. Kwemeza ko kugumana amazi na HPMC
Kunozwa kwibanda kuri HPMC yo kugumana amazi meza bisaba gusuzuma ibintu nkibisabwa byintego, imikoranire yibindi bitekerezo, nibindi byifuzo byamazi bitabangamiye imikorere itunganya hamwe nibindi bintu byigisubizo.
Kwibanda kuri HPMC bigira ingaruka zikomeye kubuza amazi yigisubizo. Mu gihe gito, kugumana amazi ni bike; Ku rwego rwo hagati, imiterere ihamye yashyizweho kugirango ihagarike ihohoterwa ryamazi; Mugihe kinini, ingaruka ntarengwa z'amazi zigerwaho. Imirima itandukanye yo gusaba ifite ibisabwa bitandukanye kuri HPMC yibanda kubitekerezo bya HPMC, bigomba guhindurwa neza hakurikijwe ibikenewe kugirango ugere kumiterere hagati yo kugumana amazi meza no gutunganya imikorere.
Igihe cyagenwe: Gashyantare-17-2025