Ingaruka za HPMC kumikorere yo kwishyira hamwe kwa minisiteri

Myiricyubahiro MIRING irashobora kwishingikiriza kuburemere bwayo kugirango ikore urufatiro ruringaniye, runoze kandi rukomeye kuri substrate kugirango ushireho cyangwa uhuza ibindi bikoresho. Muri icyo gihe, irashobora gukora igipimo kinini no kubaka neza. Kubwibyo, amazi menshi ni ikintu cyingenzi cyane cyo kwishyira hamwe, bigomba kugira akabagumana n'amazi no guhuza amazu, nta kintu cyo guhuza amazi, kandi gifite ibiranga ubushyuhe n'ubushyuhe buke.

Mubisanzwe, kuringaniza kwishyira hamwe bisaba amazi meza, ariko amazi ya sima nyayo ni 10-12cm gusa; Mu bakoresha kasho, hydroxyPropyl methylcellse (HPMC) ni ngombwa mu mikorere yiteguye, nubwo amafaranga yo kongereranyo ari make, irashobora kunoza uburyo buhoraho, burashobora kunoza uburyo bwo kwiyongera, burashobora kunoza uburyo buhoraho, burashobora kunoza uburyo buhoraho, burashobora kunoza uburyo buhoraho, burashobora kunoza uburyo buhoraho, burashobora kunoza uburyo buhoraho, burashobora kunoza uburyo buhoraho, burashobora kunoza uburyo buhoraho, burashobora kunoza uburyo buhoraho, burashobora kunoza uburyo buhoraho, burashobora kunoza uburyo buhoraho, burashobora kunoza imikorere, imikorere yimikorere, imikorere yo kuguhira amazu. Ifite uruhare runini mu murima wa minisiteri yiteguye.

1. Kugenda

HydroxyPropyl MethylcellAlose (HPMC) ifite uruhare rukomeye mugufungiraga amazi, guhoraho n'imikorere yo kubaka minisiteri yo kwishyira hamwe. Cyane cyane nkumuntu waringaniza, amazi nimwe mubipimo ngenderwaho mugusuzuma imikorere yingirakamaro. Munsi yo kwemeza ibigize minisiteri isanzwe, amazi ya minisiteri arashobora guhinduka muguhindura ingano ya HPMC. Ariko, niba dosage ari ndende cyane, amazi ya minisiteri azagabanuka, nuko igipimo cya HPMC kigomba kugenzurwa muburyo bwumvikana.

2. Kugumana amazi

Kugumana amazi nicyitegererezo cyingenzi cyo gupima ituze ryibice byimbere muri sima zivanze na sima. Kugirango usohoze byimazeyo hydration reaction yibikoresho bya gel, umubare ushyira mu gaciro urashobora gukomeza ubuhehere muri minisiteri igihe kirekire. Muri rusange, umubare wogumana amazi wongeraho wiyongera hamwe no kwiyongera kwa HPMC. Imikorere yo kugumana amazi ya HPMC irashobora kubuza ishyaka ryinjira mumazi menshi vuba, kandi akabangamira guhumeka, kugirango tumenye ko ibidukikije bituje bitanga amazi ahagije yo kwiyongera kwa sima. Byongeye kandi, viscosiya za hydroxyPropyl methylcellsell kandi ifite uruhare runini mugusuka amazi ya minisiteri. Hejuru cyane viscosiya, icyubahiro cyiza. Mubisanzwe, ibicuruzwa bifite ubuyonguzi bwa 400mpa.s bikoreshwa ahanini mukwirinda minisiteri, bishobora kunoza imikorere ya minisiteri kandi bishobora kunoza imikorere ya minisiteri no kongera urwenya rwa minisiteri.

3. Gushiraho igihe

HPMC ifite ingaruka zimwe zidindiza kuri minisiteri. Hamwe no kwiyongera k'umuyoboro, igihe cyagenwe cya minisiteri kirangiye. Ingaruka zidindiza ya HPMC kuri sima ya Paste cyane cyane biterwa nurwego rwo gusimbuza amatsinda ya Alkyl, kandi afite umubano muto nuburemere bwayo. Urwego ruto rwa Alkyl, ingano nini ya hydroxyl, nibindi biragaragara ingaruka zidindiza. Kandi ibikubiye muri HPMC, biragaragara ko ingaruka za firime zigoye zo mu rwego rwo hambere hagamijwe kwishyurwa na sima, bityo ingaruka zidindiza nayo iragaragara.

4. Imbaraga zoroheje nimbaraga zo Guhunga

Mubisanzwe, imbaraga ni imwe mu ngingo zingenzi zisuzuma zo gukiza ingaruka za sima zishingiye ku givange. Imbaraga zikurura hamwe n'imbaraga zoroheje ya minisiteri bizagabanuka hamwe no kwiyongera kwa HPMC.

5. Imbaraga

HPMC ifite ingaruka zikomeye kumikorere ihuza miniko. HPMC ikora firime ya polymer ifite ingaruka zidasanzwe hagati ya sisitemu yicyiciro cyamazi hamwe na sima hydration ibice, biteza imbere amazi menshi hanze ya sima, bityo bifasha kugereranywa byuzuye, bityo bitera ubuziranenge. Imbaraga zo gukomera. Muri icyo gihe, yongeraho umubare ukwiye wa HPMC yongera plastike no guhinduka muri minisiteri, bigabanya ubukana bwakarere ka minisiteri hamwe na interineti, kandi bigabanya ubushobozi bwo kunyerera hagati yimikorere. Ku rugero runaka, ingaruka zo guhuza hagati ya minisiteri hamwe na substrate zizamurwa. Byongeye kandi, kubera ko HPMC ibaho muri sima ya paste, akarere kihariye bya Interifeka hamwe ninteko rusange bikozwe hagati yingingo za miriro hamwe nibicuruzwa bya hydration. Iyi interineti ikora ahantu hinzura intangarugero cyane byoroshye kandi bidakomeye. Kubwibyo, minisiteri ifite imbaraga zikomeye zo guhuza.